LRRC25
leucine rich repeat containing 25
Summary
Predicted to act upstream of or within several processes, including canonical NF-kappaB signal transduction; connective tissue replacement involved in inflammatory response wound healing; and response to angiotensin. Located in cytosol; endoplasmic reticulum; and microtubule cytoskeleton. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants23 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs2512892713 | 19:18,502,913 | C/T | — | uncertain significance |
| rs45543339 | 19:18,503,194 | C/G | — | — |
| rs772470201 | 19:18,507,052 | T/C | — | uncertain significance |
| rs34439430 | 19:18,507,074 | G/T | — | benign |
| rs780060558 | 19:18,507,088 | G/A | — | uncertain significance |
| rs557669117 | 19:18,507,089 | G/C | — | uncertain significance |
| rs142331141 | 19:18,507,099 | G/T | — | uncertain significance |
| rs747853006 | 19:18,507,100 | C/T | — | uncertain significance |
| rs1210863184 | 19:18,507,112 | T/C | — | uncertain significance |
| rs1465139600 | 19:18,507,116 | G/A | — | uncertain significance |
| rs200210384 | 19:18,507,136 | G/C | — | uncertain significance |
| rs1230327268 | 19:18,507,173 | G/C | — | uncertain significance |
| rs2512896923 | 19:18,507,185 | T/C | — | uncertain significance |
| rs373989836 | 19:18,507,193 | C/T | — | uncertain significance |
| rs541540034 | 19:18,507,302 | C/T | — | uncertain significance |
| rs759345769 | 19:18,507,344 | T/C | — | uncertain significance |
| rs1971973109 | 19:18,507,422 | A/G | — | uncertain significance |
| rs2512897519 | 19:18,507,473 | C/T | — | uncertain significance |
| rs2512897524 | 19:18,507,476 | C/T | — | uncertain significance |
| rs749097669 | 19:18,507,610 | T/C | — | uncertain significance |
| rs765606507 | 19:18,507,688 | G/A | — | uncertain significance |
| rs141746674 | 19:18,507,739 | G/A | — | likely benign |
| rs150554036 | 19:18,507,740 | G/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.