LSM2
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
Summary
This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 19. [provided by RefSeq, Nov 2011]
Known Variants11 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs1144710 | 6:31,765,864 | T/A | upstream gene variant | — |
| rs2736425 | 6:31,765,984 | G/A | upstream gene variant | — |
| rs2763980 | 6:31,766,660 | C/T | upstream gene variant | — |
| rs117127906 | 6:31,766,751 | G/T | upstream gene variant | — |
| rs13207465 | 6:31,768,055 | G/T | upstream gene variant | — |
| rs35604230 | 6:31,768,305 | G/A | upstream gene variant | — |
| rs681331 | 6:31,768,799 | A/C | intron variant | — |
| rs73400280 | 6:31,769,479 | G/A | intron variant | — |
| rs625421 | 6:31,772,093 | C/T | — | — |
| rs184004642 | 6:31,773,521 | T/C | downstream gene variant | — |
| rs572878332 | 6:31,776,398 | T/A | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.