LYVE1

lymphatic vessel endothelial hyaluronan receptor 1

Summary

This gene encodes a type I integral membrane glycoprotein. The encoded protein acts as a receptor and binds to both soluble and immobilized hyaluronan. This protein may function in lymphatic hyaluronan transport and have a role in tumor metastasis. [provided by RefSeq, Jul 2008]

Known Variants26 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs2539650910	11:10,580,696	T/C	—	uncertain significance
rs1850366294	11:10,580,704	T/A	—	uncertain significance
rs147714545	11:10,580,716	G/C	—	uncertain significance
rs746141063	11:10,580,761	T/C	—	uncertain significance
rs117443264	11:10,580,792	C/T	missense variant	—
rs140605904	11:10,581,399	C/T	—	uncertain significance
rs771243144	11:10,581,432	G/A	—	uncertain significance
rs1029365465	11:10,582,054	C/A	—	uncertain significance
rs746240000	11:10,582,093	G/C	—	uncertain significance
rs2539654128	11:10,582,113	G/T	—	uncertain significance
rs747770568	11:10,582,116	C/A	—	uncertain significance
rs376908330	11:10,582,125	A/G	—	likely benign
rs2539654217	11:10,582,147	T/C	—	uncertain significance
rs779489417	11:10,582,194	G/A	—	uncertain significance
rs949259277	11:10,585,510	G/T	—	uncertain significance
rs140328426	11:10,585,528	G/C	—	uncertain significance
rs183775500	11:10,585,552	A/G	—	uncertain significance
rs147788904	11:10,585,573	G/A	—	likely benign
rs139582089	11:10,585,601	C/T	—	uncertain significance
rs754510091	11:10,585,780	G/A	—	uncertain significance
rs143843236	11:10,585,828	G/T	—	uncertain significance
rs375834783	11:10,585,843	G/C	—	uncertain significance
rs764143601	11:10,585,891	A/G	—	uncertain significance
rs1194262676	11:10,589,998	C/T	—	uncertain significance
rs1463361432	11:10,590,040	T/G	—	uncertain significance
rs1269805849	11:10,590,045	G/A	—	uncertain significance

Gene information from NCBI Gene. Variant classifications from ClinVar.