MAGOH
mago homolog, exon junction complex subunit
Summary
Drosophila that have mutations in their mago nashi (grandchildless) gene produce progeny with defects in germplasm assembly and germline development. This gene encodes the mammalian mago nashi homolog. In mammals, mRNA expression is not limited to the germ plasm, but is expressed ubiquitously in adult tissues and can be induced by serum stimulation of quiescent fibroblasts. [provided by RefSeq, Jul 2008]
Known Variants4 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs12082305 | 1:53,693,627 | T/G | downstream gene variant | — |
| rs1030375782 | 1:53,694,553 | T/C | — | uncertain significance |
| rs13375749 | 1:53,695,882 | T/C | intron variant | — |
| rs763619997 | 1:53,699,309 | T/C | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.