MAP7
microtubule associated protein 7
Summary
The product of this gene is a microtubule-associated protein that is predominantly expressed in cells of epithelial origin. Microtubule-associated proteins are thought to be involved in microtubule dynamics, which is essential for cell polarization and differentiation. This protein has been shown to be able to stabilize microtubules, and may serve to modulate microtubule functions. Studies of the related mouse protein also suggested an essential role in microtubule function required for spermatogenesis. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Known Variants58 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs1043058644 | 6:136,667,108 | C/T | — | uncertain significance |
| rs2546642259 | 6:136,677,851 | T/G | — | uncertain significance |
| rs759784219 | 6:136,680,984 | G/A | — | uncertain significance |
| rs559894538 | 6:136,680,985 | C/A | — | uncertain significance |
| rs147645484 | 6:136,681,130 | C/T | — | likely benign |
| rs960406204 | 6:136,681,845 | T/C | — | uncertain significance |
| rs757742259 | 6:136,682,154 | C/A | — | uncertain significance |
| rs34607647 | 6:136,682,177 | C/T | — | uncertain significance |
| rs773760531 | 6:136,682,201 | C/G | — | uncertain significance |
| rs148141271 | 6:136,682,226 | G/C | — | uncertain significance |
| rs896174811 | 6:136,682,249 | C/A | — | uncertain significance |
| rs770525505 | 6:136,682,250 | G/A | — | uncertain significance |
| rs138707784 | 6:136,682,265 | G/C | — | uncertain significance |
| rs1792633468 | 6:136,682,276 | C/T | — | uncertain significance |
| rs757233415 | 6:136,683,702 | G/A | — | uncertain significance |
| rs765075900 | 6:136,683,703 | C/T | — | uncertain significance |
| rs369457560 | 6:136,683,774 | G/A | — | uncertain significance |
| rs201869040 | 6:136,686,981 | G/A | — | uncertain significance |
| rs777956137 | 6:136,686,993 | G/T | — | uncertain significance |
| rs1374226394 | 6:136,687,112 | G/A | — | uncertain significance |
| rs111623909 | 6:136,687,124 | C/T | — | uncertain significance |
| rs371652446 | 6:136,687,474 | G/A | — | uncertain significance |
| rs747862616 | 6:136,687,477 | C/T | — | uncertain significance |
| rs184424340 | 6:136,687,492 | G/A | — | uncertain significance |
| rs377171374 | 6:136,687,502 | T/C | — | uncertain significance |
| rs2546728369 | 6:136,687,531 | G/T | — | uncertain significance |
| rs150650551 | 6:136,693,745 | A/T | — | benign |
| rs749626540 | 6:136,693,769 | C/T | — | uncertain significance |
| rs543935729 | 6:136,698,940 | G/A | — | uncertain significance |
| rs200010762 | 6:136,698,944 | G/A | — | uncertain significance |
| rs149503470 | 6:136,698,952 | G/A | — | uncertain significance |
| rs2546811376 | 6:136,699,000 | C/T | — | uncertain significance |
| rs375908348 | 6:136,704,866 | C/T | — | uncertain significance |
| rs750885029 | 6:136,704,917 | G/T | — | uncertain significance |
| rs2546885476 | 6:136,709,569 | C/T | — | uncertain significance |
| rs756424207 | 6:136,709,575 | G/C | — | uncertain significance |
| rs148680029 | 6:136,709,581 | C/T | — | uncertain significance |
| rs369203483 | 6:136,709,588 | G/C | — | uncertain significance |
| rs375795407 | 6:136,709,618 | T/C | — | uncertain significance |
| rs769695371 | 6:136,709,626 | C/T | — | uncertain significance |
| rs369644416 | 6:136,709,645 | G/A | — | uncertain significance |
| rs376901368 | 6:136,710,541 | C/G | — | uncertain significance |
| rs776074208 | 6:136,710,544 | C/T | — | uncertain significance |
| rs144407106 | 6:136,710,582 | C/T | — | likely benign |
| rs769178325 | 6:136,710,620 | G/C | — | uncertain significance |
| rs533989934 | 6:136,710,652 | G/C | — | uncertain significance |
| rs549882772 | 6:136,720,769 | G/A | — | — |
| rs775441643 | 6:136,732,768 | C/G | — | uncertain significance |
| rs141805814 | 6:136,732,772 | C/T | — | uncertain significance |
| rs1473859887 | 6:136,732,781 | C/T | — | uncertain significance |
| rs138281942 | 6:136,732,791 | G/A | — | uncertain significance |
| rs372505270 | 6:136,732,799 | C/T | — | uncertain significance |
| rs143250781 | 6:136,732,829 | G/A | — | uncertain significance |
| rs757722809 | 6:136,742,932 | C/T | — | uncertain significance |
| rs1827692114 | 6:136,847,046 | C/A | — | uncertain significance |
| rs771532911 | 6:136,847,074 | T/C | — | uncertain significance |
| rs78302547 | 6:136,860,353 | A/C | intron variant | — |
| rs773537487 | 6:136,871,497 | G/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.