MARCHF7
membrane associated ring-CH-type finger 7
Summary
MARCH7 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Mar 2010]
Known Variants47 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs57562635 | 2:160,576,281 | G/A | intron variant | — |
| rs140055725 | 2:160,585,617 | C/A | — | uncertain significance |
| rs200535190 | 2:160,585,643 | A/G | — | uncertain significance |
| rs149235126 | 2:160,599,594 | C/T | — | uncertain significance |
| rs139916486 | 2:160,599,647 | C/T | — | uncertain significance |
| rs761378095 | 2:160,599,648 | G/A | — | uncertain significance |
| rs973139432 | 2:160,599,725 | G/T | — | uncertain significance |
| rs780090799 | 2:160,599,733 | A/C | — | uncertain significance |
| rs1704363949 | 2:160,599,747 | G/A | — | uncertain significance |
| rs59231221 | 2:160,600,414 | G/A | regulatory region variant | — |
| rs56014508 | 2:160,600,750 | C/T | intron variant | — |
| rs10196220 | 2:160,601,931 | C/G | — | — |
| rs778493903 | 2:160,602,394 | A/C | — | uncertain significance |
| rs753934115 | 2:160,602,422 | G/A | — | uncertain significance |
| rs540482309 | 2:160,604,376 | G/A | — | uncertain significance |
| rs141778200 | 2:160,604,391 | A/G | — | uncertain significance |
| rs772355894 | 2:160,604,470 | A/T | — | uncertain significance |
| rs76774368 | 2:160,604,514 | C/T | missense variant | — |
| rs370727541 | 2:160,604,558 | A/G | — | uncertain significance |
| rs781136569 | 2:160,604,596 | A/C | — | uncertain significance |
| rs1248470061 | 2:160,604,711 | T/G | — | uncertain significance |
| rs376007551 | 2:160,604,741 | T/G | — | uncertain significance |
| rs756806419 | 2:160,604,769 | C/T | — | uncertain significance |
| rs746320353 | 2:160,604,780 | C/T | — | uncertain significance |
| rs141446988 | 2:160,604,889 | A/G | — | uncertain significance |
| rs766857856 | 2:160,604,907 | A/C | — | uncertain significance |
| rs755335648 | 2:160,604,928 | A/G | — | uncertain significance |
| rs1177159989 | 2:160,604,943 | A/G | — | uncertain significance |
| rs1455864685 | 2:160,604,951 | C/T | — | uncertain significance |
| rs769528863 | 2:160,604,979 | G/T | — | uncertain significance |
| rs150144842 | 2:160,605,009 | G/A | — | uncertain significance |
| rs747901342 | 2:160,605,069 | T/C | — | uncertain significance |
| rs551500569 | 2:160,605,113 | A/G | — | uncertain significance |
| rs761095067 | 2:160,605,200 | G/T | — | uncertain significance |
| rs535695438 | 2:160,605,201 | C/T | — | uncertain significance |
| rs372591967 | 2:160,605,246 | C/G | — | uncertain significance |
| rs149065142 | 2:160,605,293 | G/A | — | uncertain significance |
| rs2469063739 | 2:160,605,314 | G/C | — | uncertain significance |
| rs928780473 | 2:160,605,371 | G/C | — | uncertain significance |
| rs1184405137 | 2:160,608,921 | T/C | — | uncertain significance |
| rs74619980 | 2:160,611,304 | A/G | intron variant | — |
| rs1451130857 | 2:160,615,799 | G/A | — | uncertain significance |
| rs1008697985 | 2:160,615,804 | T/G | — | uncertain significance |
| rs10929951 | 2:160,617,226 | G/T | — | — |
| rs1385928982 | 2:160,619,418 | C/G | — | uncertain significance |
| rs756184632 | 2:160,619,502 | C/G | — | uncertain significance |
| rs138164180 | 2:160,621,167 | C/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.