MBOAT2
membrane bound glycerophospholipid O-acyltransferase 2
Summary
Enables 1-acylglycerophosphocholine O-acyltransferase activity; 1-acylglycerophosphoethanolamine O-acyltransferase activity; and 1-acylglycerophosphoserine O-acyltransferase activity. Involved in phosphatidylcholine acyl-chain remodeling; phosphatidylethanolamine acyl-chain remodeling; and phosphatidylserine acyl-chain remodeling. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants20 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs143390233 | 2:8,998,855 | T/C | — | likely benign |
| rs201954366 | 2:8,998,970 | T/C | — | uncertain significance |
| rs1376965890 | 2:8,998,976 | T/C | — | uncertain significance |
| rs376215272 | 2:9,000,804 | T/C | — | uncertain significance |
| rs150340101 | 2:9,002,851 | C/G | — | uncertain significance |
| rs187474422 | 2:9,004,345 | A/T | — | uncertain significance |
| rs753835262 | 2:9,004,357 | G/A | — | uncertain significance |
| rs764306370 | 2:9,008,616 | C/A | — | uncertain significance |
| rs750186080 | 2:9,008,617 | G/A | — | uncertain significance |
| rs183412132 | 2:9,008,986 | G/A | intron variant | — |
| rs768843029 | 2:9,013,301 | T/C | — | likely benign |
| rs202062819 | 2:9,013,307 | T/C | — | uncertain significance |
| rs762996415 | 2:9,013,310 | G/T | — | uncertain significance |
| rs760240347 | 2:9,013,378 | A/C | — | uncertain significance |
| rs2527303678 | 2:9,017,176 | G/T | — | uncertain significance |
| rs1158930325 | 2:9,017,177 | T/C | — | likely benign |
| rs542141791 | 2:9,022,687 | G/A | — | uncertain significance |
| rs766486740 | 2:9,048,803 | C/T | — | likely benign |
| rs930214033 | 2:9,048,823 | C/A | — | uncertain significance |
| rs1471364240 | 2:9,098,719 | C/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.