MED16
mediator complex subunit 16
Summary
Enables nuclear thyroid hormone receptor binding activity and transcription coactivator activity. Involved in positive regulation of transcription initiation by RNA polymerase II. Located in nucleus. Part of core mediator complex and mediator complex. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants119 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs151170454 | 19:868,109 | G/A | — | uncertain significance |
| rs534242015 | 19:868,114 | T/A | — | uncertain significance |
| rs146928647 | 19:868,127 | G/A | — | uncertain significance |
| rs2035957575 | 19:868,129 | T/C | — | uncertain significance |
| rs372252782 | 19:868,154 | A/G | — | likely benign |
| rs138793388 | 19:868,184 | C/T | — | uncertain significance |
| rs372311899 | 19:868,238 | G/A | — | uncertain significance |
| rs35040519 | 19:868,421 | G/A | — | benign |
| rs199528280 | 19:868,473 | G/A | — | uncertain significance |
| rs989995459 | 19:868,887 | G/A | — | uncertain significance |
| rs201531363 | 19:868,897 | C/T | — | uncertain significance |
| rs1178005651 | 19:868,906 | G/T | — | uncertain significance |
| rs958763084 | 19:868,908 | A/T | — | uncertain significance |
| rs2512192094 | 19:868,910 | C/G | — | uncertain significance |
| rs1437440864 | 19:868,936 | G/T | — | uncertain significance |
| rs117226930 | 19:869,287 | G/C | regulatory region variant | — |
| rs1188100993 | 19:871,054 | C/A | — | uncertain significance |
| rs774377494 | 19:871,064 | G/A | — | uncertain significance |
| rs200816964 | 19:871,088 | G/A | — | uncertain significance |
| rs373765974 | 19:871,092 | G/A | — | uncertain significance |
| rs764958390 | 19:871,106 | C/T | — | uncertain significance |
| rs752460156 | 19:871,107 | G/A | — | uncertain significance |
| rs762694444 | 19:871,110 | G/T | — | uncertain significance |
| rs555543361 | 19:871,113 | G/A | — | uncertain significance |
| rs377113997 | 19:871,131 | G/T | — | uncertain significance |
| rs34110403 | 19:871,146 | C/A | — | uncertain significance |
| rs751147997 | 19:871,167 | G/C | — | uncertain significance |
| rs2512196755 | 19:871,176 | T/C | — | uncertain significance |
| rs368424152 | 19:871,187 | C/G | — | uncertain significance |
| rs1244425481 | 19:871,219 | C/G | — | uncertain significance |
| rs373503269 | 19:871,250 | C/T | — | uncertain significance |
| rs376733954 | 19:871,251 | G/A | — | uncertain significance |
| rs2512200560 | 19:871,934 | C/G | — | uncertain significance |
| rs148428449 | 19:871,953 | G/A | — | uncertain significance |
| rs1334940919 | 19:871,994 | G/C | — | uncertain significance |
| rs866978956 | 19:872,025 | G/A | — | uncertain significance |
| rs201643609 | 19:872,045 | A/G | — | uncertain significance |
| rs372729340 | 19:872,049 | T/G | — | uncertain significance |
| rs778682095 | 19:872,072 | G/A | — | uncertain significance |
| rs140413604 | 19:872,075 | G/A | — | uncertain significance |
| rs761913910 | 19:872,088 | G/C | — | uncertain significance |
| rs866437536 | 19:873,000 | T/G | — | likely benign |
| rs191475289 | 19:873,001 | G/A | — | likely benign |
| rs369009728 | 19:873,523 | G/C | — | uncertain significance |
| rs902095170 | 19:873,525 | G/A | — | uncertain significance |
| rs1472116947 | 19:873,573 | T/C | — | uncertain significance |
| rs781113104 | 19:873,580 | T/C | — | uncertain significance |
| rs61738004 | 19:875,245 | G/A | — | benign |
| rs199855041 | 19:875,272 | G/A | — | likely benign |
| rs759314391 | 19:875,339 | G/A | — | uncertain significance |
| rs1411287295 | 19:875,342 | G/T | — | uncertain significance |
| rs2036205500 | 19:875,347 | G/C | — | uncertain significance |
| rs756660089 | 19:875,352 | C/T | — | uncertain significance |
| rs1046972903 | 19:875,358 | G/C | — | uncertain significance |
| rs148896515 | 19:875,364 | G/C | — | uncertain significance |
| rs2512211366 | 19:875,372 | T/C | — | uncertain significance |
| rs1385846825 | 19:875,403 | G/A | — | uncertain significance |
| rs754354623 | 19:875,405 | G/A | — | uncertain significance |
| rs368293469 | 19:875,430 | T/C | — | uncertain significance |
| rs899619828 | 19:875,441 | C/T | — | uncertain significance |
| rs376368245 | 19:875,442 | G/A | — | uncertain significance |
| rs1651886 | 19:876,641 | T/C | intron variant | — |
| rs111469573 | 19:876,882 | C/A | intron variant | — |
| rs2512216264 | 19:876,968 | C/A | — | uncertain significance |
| rs1366059277 | 19:877,000 | T/C | — | uncertain significance |
| rs72984032 | 19:877,009 | C/T | — | uncertain significance |
| rs753980174 | 19:877,042 | T/G | — | uncertain significance |
| rs2512216610 | 19:877,050 | A/G | — | uncertain significance |
| rs761072743 | 19:877,120 | G/A | — | uncertain significance |
| rs751511690 | 19:877,143 | G/A | — | uncertain significance |
| rs763166625 | 19:877,168 | G/A | — | uncertain significance |
| rs751604368 | 19:877,174 | C/T | — | likely benign |
| rs1617214 | 19:877,437 | G/A | — | — |
| rs200085016 | 19:879,947 | C/T | — | likely benign |
| rs375553045 | 19:879,966 | C/T | — | uncertain significance |
| rs779733947 | 19:880,011 | G/A | — | uncertain significance |
| rs568311248 | 19:880,014 | C/T | — | uncertain significance |
| rs771718305 | 19:880,017 | C/T | — | likely benign |
| rs146740386 | 19:880,023 | G/A | — | uncertain significance |
| rs371415029 | 19:880,034 | A/G | — | uncertain significance |
| rs764524747 | 19:880,061 | G/T | — | uncertain significance |
| rs756281329 | 19:880,064 | G/A | — | uncertain significance |
| rs144143613 | 19:880,080 | C/T | — | uncertain significance |
| rs995330005 | 19:880,083 | C/G | — | uncertain significance |
| rs545399512 | 19:880,125 | C/T | — | uncertain significance |
| rs780747728 | 19:880,142 | G/A | — | uncertain significance |
| rs2512232548 | 19:881,615 | G/A | — | uncertain significance |
| rs146721272 | 19:884,907 | G/A | — | likely benign |
| rs978426020 | 19:884,929 | T/A | — | uncertain significance |
| rs1456674484 | 19:884,980 | C/T | — | uncertain significance |
| rs2512238747 | 19:884,993 | A/T | — | uncertain significance |
| rs769010211 | 19:884,995 | G/A | — | uncertain significance |
| rs142466928 | 19:885,760 | G/A | — | likely benign |
| rs761731274 | 19:885,841 | C/T | — | uncertain significance |
| rs921446134 | 19:885,864 | G/C | — | uncertain significance |
| rs773847580 | 19:886,000 | C/T | — | uncertain significance |
| rs1345970209 | 19:886,008 | G/A | — | uncertain significance |
| rs954441194 | 19:886,021 | G/A | — | uncertain significance |
| rs769385094 | 19:886,047 | G/A | — | uncertain significance |
| rs1599341574 | 19:886,050 | A/G | — | uncertain significance |
Showing 100 of 119 variants. Use the SNP search for the full list.
Gene information from NCBI Gene. Variant classifications from ClinVar.