MGAM

maltase-glucoamylase

Summary

This gene encodes maltase-glucoamylase, which is a brush border membrane enzyme that plays a role in the final steps of digestion of starch. The protein has two catalytic sites identical to those of sucrase-isomaltase, but the proteins are only 59% homologous. Both are members of glycosyl hydrolase family 31, which has a variety of substrate specificities. [provided by RefSeq, Jul 2008]

Known Variants159 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs972193872	7:141,705,359	C/G	—	uncertain significance
rs201144916	7:141,705,413	T/C	—	likely benign
rs145706810	7:141,705,462	G/T	—	likely benign
rs2485774038	7:141,708,372	C/G	—	uncertain significance
rs2485774161	7:141,708,377	A/G	—	uncertain significance
rs571920896	7:141,708,383	C/A	—	uncertain significance
rs782638645	7:141,708,408	A/G	—	uncertain significance
rs2485774983	7:141,708,422	G/C	—	uncertain significance
rs373889066	7:141,708,435	T/C	—	uncertain significance
rs748580642	7:141,708,495	C/A	—	uncertain significance
rs782730354	7:141,719,014	C/T	—	uncertain significance
rs191137461	7:141,720,785	C/T	—	uncertain significance
rs1474856078	7:141,720,825	A/G	—	uncertain significance
rs781807541	7:141,720,870	G/A	—	uncertain significance
rs957482156	7:141,721,425	G/A	—	uncertain significance
rs376468703	7:141,721,482	A/C	—	uncertain significance
rs781819632	7:141,721,531	G/A	—	uncertain significance
rs368544175	7:141,722,104	C/A	—	uncertain significance
rs782014529	7:141,722,107	G/C	—	uncertain significance
rs1272804758	7:141,722,181	G/C	—	uncertain significance
rs1554459281	7:141,722,232	C/T	—	uncertain significance
rs1401471656	7:141,724,948	G/A	—	uncertain significance
rs199961575	7:141,726,950	C/T	—	uncertain significance
rs2485951716	7:141,726,956	A/G	—	uncertain significance
rs1042240078	7:141,726,975	T/C	—	uncertain significance
rs1335380765	7:141,727,476	G/A	—	uncertain significance
rs184092742	7:141,727,485	G/A	—	likely benign
rs200834950	7:141,727,489	A/G	—	uncertain significance
rs377442966	7:141,727,503	G/A	—	uncertain significance
rs188481752	7:141,727,515	C/T	—	likely benign
rs782056253	7:141,730,216	G/A	—	uncertain significance
rs2485979001	7:141,730,252	A/G	—	uncertain significance
rs142037158	7:141,730,279	C/G	—	uncertain significance
rs782579825	7:141,730,458	C/G	—	uncertain significance
rs781979872	7:141,732,634	G/A	—	uncertain significance
rs782167135	7:141,734,094	C/G	—	uncertain significance
rs191698936	7:141,734,168	C/T	—	likely benign
rs183598889	7:141,734,169	G/A	—	uncertain significance
rs1426103510	7:141,734,478	A/G	—	uncertain significance
rs1807827217	7:141,734,508	T/G	—	uncertain significance
rs372476876	7:141,734,529	C/T	—	uncertain significance
rs551921132	7:141,734,553	A/G	—	uncertain significance
rs190777514	7:141,734,593	A/C	—	likely benign
rs782764005	7:141,734,604	C/G	—	uncertain significance
rs201866973	7:141,734,608	C/T	—	likely benign
rs374646574	7:141,736,023	C/T	—	uncertain significance
rs367841743	7:141,736,048	A/G	—	uncertain significance
rs74975727	7:141,736,643	T/G	—	uncertain significance
rs781838519	7:141,736,713	C/G	—	uncertain significance
rs782240946	7:141,736,734	G/T	—	uncertain significance
rs201786618	7:141,738,370	G/T	—	uncertain significance
rs2486063680	7:141,740,518	T/A	—	likely benign
rs374820212	7:141,740,562	A/G	—	uncertain significance
rs187975007	7:141,740,580	T/C	—	uncertain significance
rs373524046	7:141,740,600	G/C	—	uncertain significance
rs367922659	7:141,747,662	G/C	—	uncertain significance
rs1016579416	7:141,750,046	A/G	—	uncertain significance
rs768578658	7:141,750,066	T/G	—	uncertain significance
rs201733895	7:141,750,500	C/T	—	uncertain significance
rs749949340	7:141,750,501	G/A	—	uncertain significance
rs374204300	7:141,750,513	A/C	—	uncertain significance
rs200893409	7:141,750,543	A/G	—	uncertain significance
rs775571398	7:141,750,591	G/C	—	uncertain significance
rs115785937	7:141,750,601	A/G	—	likely benign
rs1810875477	7:141,750,603	T/C	—	uncertain significance
rs575790209	7:141,750,615	G/A	—	uncertain significance
rs199621773	7:141,752,199	A/G	—	conflicting classifications of pathogenicity
rs199504784	7:141,752,230	G/A	—	uncertain significance
rs2486287767	7:141,752,241	T/A	—	uncertain significance
rs565688553	7:141,752,591	A/G	—	likely benign
rs779588141	7:141,752,629	C/T	—	likely benign
rs759597075	7:141,752,690	A/C	—	uncertain significance
rs187645172	7:141,752,722	A/G	—	uncertain significance
rs763035134	7:141,752,738	T/A	—	uncertain significance
rs752471950	7:141,752,757	C/G	—	uncertain significance
rs761137030	7:141,752,770	A/T	—	uncertain significance
rs372065250	7:141,754,594	C/T	—	uncertain significance
rs566877632	7:141,754,611	A/G	—	likely benign
rs201314573	7:141,754,635	C/G	—	uncertain significance
rs201221721	7:141,754,695	A/G	—	uncertain significance
rs146671003	7:141,755,418	C/T	—	likely benign
rs185758556	7:141,755,462	G/C	—	likely benign
rs1404099248	7:141,755,508	C/G	—	likely benign
rs1811496059	7:141,755,858	G/T	—	uncertain significance
rs1811496746	7:141,755,860	G/A	—	uncertain significance
rs200314253	7:141,756,650	C/T	—	uncertain significance
rs202179894	7:141,756,705	G/A	—	uncertain significance
rs768217462	7:141,756,713	C/A	—	uncertain significance
rs191199615	7:141,759,282	A/G	—	uncertain significance
rs1294587147	7:141,759,329	C/T	—	uncertain significance
rs2961074	7:141,759,340	T/C	—	likely benign
rs1340116053	7:141,759,350	G/C	—	uncertain significance
rs769721754	7:141,759,363	G/C	—	uncertain significance
rs774233528	7:141,759,384	G/A	—	uncertain significance
rs374679841	7:141,759,684	A/G	—	uncertain significance
rs184974986	7:141,759,704	C/T	—	uncertain significance
rs1418212410	7:141,759,728	A/T	—	uncertain significance
rs371809571	7:141,759,730	C/G	—	uncertain significance
rs376193103	7:141,759,737	C/A	—	uncertain significance
rs1441650508	7:141,759,747	G/A	—	uncertain significance

Showing 100 of 159 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.