MORF4L1
mortality factor 4 like 1
Summary
Predicted to enable chromatin binding activity. Involved in double-strand break repair via homologous recombination; positive regulation of double-strand break repair via homologous recombination; and regulation of cell cycle. Located in nuclear speck. Part of NuA4 histone acetyltransferase complex; Sin3-type complex; and nucleosome. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants15 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs2505064864 | 15:79,165,387 | A/G | — | uncertain significance |
| rs553979132 | 15:79,168,749 | T/A | — | — |
| rs62013160 | 15:79,169,087 | C/T | intron variant | — |
| rs562473580 | 15:79,169,207 | C/T | — | — |
| rs758226002 | 15:79,177,320 | G/C | — | uncertain significance |
| rs200340713 | 15:79,177,328 | C/T | — | uncertain significance |
| rs2505105986 | 15:79,177,340 | T/A | — | likely benign |
| rs140562479 | 15:79,177,383 | C/G | — | uncertain significance |
| rs1320280914 | 15:79,177,409 | C/A | — | uncertain significance |
| rs962319619 | 15:79,178,524 | T/C | — | uncertain significance |
| rs376291639 | 15:79,183,844 | G/C | — | uncertain significance |
| rs774301883 | 15:79,183,855 | A/G | — | uncertain significance |
| rs28408315 | 15:79,185,180 | G/A | intron variant | — |
| rs186560594 | 15:79,187,225 | A/G | — | uncertain significance |
| rs2056901939 | 15:79,189,339 | A/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.