MOSMO
modulator of smoothened
Summary
Predicted to be involved in negative regulation of smoothened signaling pathway; regulation of neuron differentiation; and regulation of protein stability. Predicted to act upstream of or within several processes, including chordate embryonic development; embryonic limb morphogenesis; and smoothened signaling pathway. Predicted to be located in plasma membrane. Predicted to be active in Golgi apparatus and ciliary membrane. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants3 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs12930166 | 16:22,025,297 | A/G | intron variant | — |
| rs746748071 | 16:22,086,877 | C/G | — | uncertain significance |
| rs1471374168 | 16:22,086,945 | A/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.