MTCL1

microtubule crosslinking factor 1

Summary

Enables microtubule binding activity. Involved in chromosome segregation. Located in kinetochore; midbody; and spindle. [provided by Alliance of Genome Resources, Jul 2025]

Known Variants175 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs151052217	18:8,706,486	G/A	—	benign
rs1408233142	18:8,706,589	C/G	—	uncertain significance
rs2510211807	18:8,718,497	C/T	—	pathogenic
rs374198736	18:8,718,524	G/A	—	uncertain significance
rs1393920076	18:8,718,578	A/G	—	uncertain significance
rs541450483	18:8,720,427	G/A	—	uncertain significance
rs373625990	18:8,720,469	A/G	—	uncertain significance
rs745652783	18:8,783,565	C/G	—	uncertain significance
rs748729444	18:8,783,615	G/A	—	uncertain significance
rs144955054	18:8,783,649	A/G	—	uncertain significance
rs2510789322	18:8,783,653	G/T	—	uncertain significance
rs1203563502	18:8,783,726	G/A	—	uncertain significance
rs554525790	18:8,783,735	C/G	—	uncertain significance
rs766257022	18:8,783,777	C/T	—	uncertain significance
rs758581749	18:8,783,807	C/T	—	uncertain significance
rs199899364	18:8,783,838	G/A	—	uncertain significance
rs558326608	18:8,783,853	G/A	—	uncertain significance
rs140796802	18:8,783,862	C/G	—	uncertain significance
rs201079606	18:8,783,867	C/T	—	uncertain significance
rs138700640	18:8,783,902	C/T	—	likely benign
rs145413531	18:8,783,936	C/T	—	uncertain significance
rs755313432	18:8,783,971	G/C	—	uncertain significance
rs746633017	18:8,783,975	C/T	—	uncertain significance
rs770388585	18:8,783,976	G/A	—	uncertain significance
rs780158820	18:8,784,053	C/T	—	uncertain significance
rs996577116	18:8,784,081	C/G	—	uncertain significance
rs373564262	18:8,784,086	C/T	—	uncertain significance
rs1233866915	18:8,784,092	G/A	—	uncertain significance
rs766408369	18:8,784,095	G/A	—	uncertain significance
rs200063005	18:8,784,105	C/A	—	uncertain significance
rs1437228101	18:8,784,114	A/C	—	uncertain significance
rs376804537	18:8,784,136	G/T	—	uncertain significance
rs114316007	18:8,784,174	T/A	—	likely benign
rs2510798293	18:8,784,230	C/T	—	uncertain significance
rs189338832	18:8,784,258	G/A	—	uncertain significance
rs199867297	18:8,784,282	C/T	—	uncertain significance
rs149027252	18:8,784,314	C/T	—	uncertain significance
rs201398082	18:8,784,315	G/A	—	uncertain significance
rs918272	18:8,784,370	A/T	—	benign
rs1425001030	18:8,784,440	C/T	—	uncertain significance
rs2510803284	18:8,784,482	A/C	—	uncertain significance
rs138167149	18:8,784,487	C/T	—	likely benign
rs776564095	18:8,784,488	G/A	—	uncertain significance
rs115973534	18:8,784,506	C/T	—	uncertain significance
rs147236744	18:8,784,510	C/T	—	uncertain significance
rs201898483	18:8,784,518	C/T	—	uncertain significance
rs115077293	18:8,784,555	C/T	missense variant	—
rs200525720	18:8,784,563	C/T	—	uncertain significance
rs150698375	18:8,784,567	G/C	—	likely benign
rs139950675	18:8,784,582	C/T	—	uncertain significance
rs763148665	18:8,784,599	G/T	—	uncertain significance
rs2510806271	18:8,784,636	C/A	—	uncertain significance
rs766724340	18:8,784,647	G/A	—	uncertain significance
rs34690009	18:8,784,665	A/G	—	benign
rs2510807154	18:8,784,685	G/C	—	uncertain significance
rs947990141	18:8,784,710	A/G	—	uncertain significance
rs201511046	18:8,784,713	C/T	—	uncertain significance
rs143118025	18:8,784,717	T/C	—	uncertain significance
rs765773221	18:8,784,743	C/T	—	uncertain significance
rs778758980	18:8,784,759	C/T	—	uncertain significance
rs201915762	18:8,784,785	G/A	—	uncertain significance
rs150423289	18:8,784,791	C/T	—	uncertain significance
rs765984024	18:8,784,803	A/G	—	likely benign
rs375168888	18:8,784,834	A/G	—	uncertain significance
rs778187815	18:8,785,965	T/G	—	uncertain significance
rs1235737279	18:8,785,988	C/T	—	uncertain significance
rs201426677	18:8,786,007	G/A	—	uncertain significance
rs201927020	18:8,786,012	G/A	—	likely benign
rs764603373	18:8,786,013	C/T	—	uncertain significance
rs536482836	18:8,786,016	G/A	—	uncertain significance
rs200309875	18:8,786,030	C/T	—	uncertain significance
rs377158398	18:8,786,033	G/A	—	uncertain significance
rs770066213	18:8,786,039	G/A	—	uncertain significance
rs368739590	18:8,786,058	G/A	—	uncertain significance
rs770336713	18:8,793,003	G/C	—	uncertain significance
rs1393899365	18:8,793,006	C/T	—	uncertain significance
rs1034844007	18:8,793,018	C/A	—	uncertain significance
rs546611939	18:8,793,089	A/T	—	uncertain significance
rs139078896	18:8,793,104	A/G	—	uncertain significance
rs1300309351	18:8,796,269	C/G	—	uncertain significance
rs150964075	18:8,796,354	G/A	—	uncertain significance
rs8085873	18:8,796,364	G/A	—	benign
rs1421550969	18:8,796,440	G/A	—	uncertain significance
rs569735	18:8,797,487	C/G	—	—
rs528666485	18:8,798,122	C/T	—	uncertain significance
rs115906443	18:8,798,131	C/T	—	uncertain significance
rs141478791	18:8,798,156	C/T	—	likely benign
rs1477579552	18:8,798,194	T/C	—	uncertain significance
rs757137651	18:8,798,203	G/A	—	uncertain significance
rs141567899	18:8,798,218	C/G	—	likely benign
rs200421486	18:8,798,252	G/A	—	uncertain significance
rs114488174	18:8,798,263	G/A	—	likely benign
rs763687681	18:8,798,264	C/T	—	uncertain significance
rs2076320170	18:8,806,966	G/A	—	uncertain significance
rs114287451	18:8,807,035	G/A	—	likely benign
rs746329016	18:8,807,048	G/A	—	uncertain significance
rs745312691	18:8,813,022	G/A	—	likely benign
rs768641614	18:8,813,126	C/T	—	likely benign
rs146388364	18:8,813,142	C/T	—	uncertain significance
rs770901668	18:8,813,147	G/A	—	likely benign

Showing 100 of 175 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.