N4BP1
NEDD4 binding protein 1
Summary
Enables RNA nuclease activity; mRNA binding activity; and ubiquitin binding activity. Involved in cellular response to UV and negative regulation of viral genome replication. Predicted to be located in cytosol and nucleolus. Predicted to be active in PML body. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants43 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs2506281587 | 16:48,576,867 | G/C | — | uncertain significance |
| rs1295050845 | 16:48,576,945 | G/C | — | uncertain significance |
| rs2506281984 | 16:48,576,970 | G/A | — | uncertain significance |
| rs148110587 | 16:48,577,065 | C/T | — | likely benign |
| rs375239847 | 16:48,577,071 | G/A | — | uncertain significance |
| rs2506282551 | 16:48,577,083 | C/T | — | uncertain significance |
| rs762282239 | 16:48,577,162 | G/A | — | uncertain significance |
| rs752992795 | 16:48,582,770 | T/A | — | — |
| rs7187513 | 16:48,591,638 | T/C | upstream gene variant | — |
| rs748639228 | 16:48,594,690 | T/A | — | uncertain significance |
| rs200353639 | 16:48,594,710 | G/A | — | uncertain significance |
| rs367947146 | 16:48,594,798 | T/C | — | uncertain significance |
| rs201209953 | 16:48,594,806 | G/C | — | uncertain significance |
| rs781303949 | 16:48,594,900 | G/A | — | uncertain significance |
| rs34545922 | 16:48,594,916 | T/C | — | benign |
| rs1005434447 | 16:48,595,008 | G/A | — | uncertain significance |
| rs769957961 | 16:48,595,070 | G/C | — | uncertain significance |
| rs773832503 | 16:48,595,125 | A/T | — | uncertain significance |
| rs752226610 | 16:48,595,152 | T/C | — | likely benign |
| rs1455621420 | 16:48,595,301 | G/A | — | likely benign |
| rs760607771 | 16:48,595,436 | G/A | — | uncertain significance |
| rs2506323824 | 16:48,595,464 | C/T | — | uncertain significance |
| rs746933170 | 16:48,595,530 | T/C | — | uncertain significance |
| rs373702319 | 16:48,595,620 | C/T | — | uncertain significance |
| rs2506324751 | 16:48,595,693 | A/C | — | uncertain significance |
| rs200436019 | 16:48,595,709 | C/T | — | uncertain significance |
| rs2506324955 | 16:48,595,740 | C/T | — | uncertain significance |
| rs775378344 | 16:48,595,772 | A/G | — | uncertain significance |
| rs375706424 | 16:48,595,791 | G/A | — | likely benign |
| rs1963863808 | 16:48,595,799 | T/C | — | uncertain significance |
| rs780959827 | 16:48,595,845 | T/C | — | uncertain significance |
| rs538474015 | 16:48,596,240 | T/A | — | uncertain significance |
| rs201703173 | 16:48,596,268 | T/C | — | uncertain significance |
| rs370038322 | 16:48,596,309 | C/T | — | uncertain significance |
| rs6500395 | 16:48,621,402 | T/C | downstream gene variant | — |
| rs11643726 | 16:48,623,226 | C/T | downstream gene variant | — |
| rs2506429699 | 16:48,643,696 | T/G | — | uncertain significance |
| rs1423344551 | 16:48,643,702 | G/T | — | uncertain significance |
| rs2506429794 | 16:48,643,714 | C/T | — | uncertain significance |
| rs2506429817 | 16:48,643,717 | C/A | — | uncertain significance |
| rs2506429823 | 16:48,643,718 | A/G | — | likely benign |
| rs1964655681 | 16:48,643,805 | T/G | — | uncertain significance |
| rs1964656558 | 16:48,643,817 | T/C | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.