NCAPD3

non-SMC condensin II complex subunit D3

Summary

Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Both condensins contain 2 invariant structural maintenance of chromosome (SMC) subunits, SMC2 (MIM 605576) and SMC4 (MIM 605575), but they contain different sets of non-SMC subunits. NCAPD3 is 1 of 3 non-SMC subunits that define condensin II (Ono et al., 2003 [PubMed 14532007]).[supplied by OMIM, Mar 2008]

Known Variants177 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs747180381	11:134,022,839	T/C	—	likely benign
rs370256378	11:134,022,853	T/A	—	uncertain significance
rs147905924	11:134,022,867	C/T	—	benign
rs531995971	11:134,022,901	T/C	—	uncertain significance
rs141510296	11:134,022,906	C/G	—	uncertain significance
rs768995468	11:134,022,910	C/T	—	uncertain significance
rs113292086	11:134,022,918	C/A	—	uncertain significance
rs1164631127	11:134,023,034	C/T	—	likely pathogenic
rs147042577	11:134,023,068	T/C	—	uncertain significance
rs747474828	11:134,023,072	C/T	—	uncertain significance
rs2497327694	11:134,023,091	T/G	—	uncertain significance
rs550480461	11:134,023,176	G/T	—	likely benign
rs1943315323	11:134,023,205	G/A	—	uncertain significance
rs1393036090	11:134,023,217	T/C	—	uncertain significance
rs763889522	11:134,023,265	A/G	—	likely benign
rs202009125	11:134,026,917	G/C	—	likely benign
rs370416114	11:134,026,928	T/C	—	uncertain significance
rs544332433	11:134,026,943	C/T	—	uncertain significance
rs35943668	11:134,026,944	T/G	—	benign
rs199849895	11:134,026,955	C/T	—	uncertain significance
rs116394634	11:134,027,834	G/A	—	benign
rs150526752	11:134,027,868	G/A	—	uncertain significance
rs368939143	11:134,027,885	C/T	—	likely benign
rs554571220	11:134,027,887	A/T	—	uncertain significance
rs372398621	11:134,027,913	C/T	—	uncertain significance
rs139534157	11:134,027,914	G/A	—	benign
rs58640467	11:134,027,922	T/G	—	benign
rs142029598	11:134,027,951	A/G	—	uncertain significance
rs201978183	11:134,028,227	G/A	—	uncertain significance
rs75941252	11:134,028,324	C/T	—	benign
rs758877192	11:134,028,342	G/C	—	likely benign
rs74796704	11:134,028,365	G/A	—	benign
rs767967565	11:134,029,782	C/T	—	uncertain significance
rs34720493	11:134,029,817	A/G	—	benign
rs768508500	11:134,029,821	G/A	—	uncertain significance
rs960929446	11:134,031,696	C/T	—	uncertain significance
rs777745472	11:134,031,729	C/A	—	uncertain significance
rs201457595	11:134,031,739	G/A	—	likely benign
rs377410057	11:134,031,750	T/C	—	uncertain significance
rs374442681	11:134,037,888	C/T	—	likely benign
rs61752298	11:134,037,918	C/T	—	likely benign
rs1046961121	11:134,037,934	G/A	—	uncertain significance
rs376124629	11:134,037,940	G/A	—	uncertain significance
rs779306612	11:134,037,944	T/C	—	uncertain significance
rs746301403	11:134,037,951	T/A	—	uncertain significance
rs758112068	11:134,037,953	C/T	—	uncertain significance
rs769683892	11:134,037,968	C/T	—	uncertain significance
rs151223701	11:134,037,977	G/C	—	uncertain significance
rs370902265	11:134,037,989	T/C	—	uncertain significance
rs1350194762	11:134,038,006	T/G	—	pathogenic
rs140260009	11:134,038,020	G/C	—	likely benign
rs780746091	11:134,038,030	G/A	—	uncertain significance
rs376286698	11:134,038,053	G/A	—	likely benign
rs774185836	11:134,038,056	C/T	—	likely benign
rs763601693	11:134,038,090	G/C	—	uncertain significance
rs567450574	11:134,038,396	T/C	—	uncertain significance
rs2497407627	11:134,038,397	T/C	—	uncertain significance
rs375953580	11:134,038,399	A/T	—	uncertain significance
rs145474083	11:134,038,422	C/T	—	likely benign
rs137924264	11:134,038,430	G/T	—	uncertain significance
rs769543926	11:134,038,494	C/G	—	uncertain significance
rs2497410235	11:134,038,822	G/A	—	likely pathogenic
rs192889859	11:134,038,906	G/T	—	uncertain significance
rs143188183	11:134,038,907	G/C	—	uncertain significance
rs765047707	11:134,038,946	G/A	—	likely benign
rs7927108	11:134,038,949	G/T	—	benign
rs10736610	11:134,041,884	C/T	upstream gene variant	—
rs183955695	11:134,043,419	C/T	coding sequence variant	—
rs569823962	11:134,043,420	G/A	coding sequence variant	—
rs151063353	11:134,046,212	C/A	—	uncertain significance
rs923626843	11:134,046,240	A/T	—	uncertain significance
rs1944165127	11:134,046,245	G/A	—	likely pathogenic
rs139669316	11:134,046,257	A/C	—	uncertain significance
rs763561623	11:134,047,125	T/C	—	uncertain significance
rs572097232	11:134,047,137	T/C	—	uncertain significance
rs2276265	11:134,047,243	T/C	—	benign
rs140066669	11:134,047,273	G/A	—	likely benign
rs150304737	11:134,047,288	G/A	—	likely benign
rs143359995	11:134,047,319	T/C	—	uncertain significance
rs770703712	11:134,047,332	C/T	—	uncertain significance
rs1043297020	11:134,048,561	G/C	—	uncertain significance
rs75363476	11:134,048,587	G/C	—	likely benign
rs765355523	11:134,048,589	G/T	—	uncertain significance
rs34739733	11:134,048,592	G/T	—	benign
rs201225237	11:134,048,594	G/A	—	likely benign
rs781447868	11:134,048,602	C/T	—	likely benign
rs1207215795	11:134,048,604	C/T	—	uncertain significance
rs143778814	11:134,048,640	C/T	—	likely benign
rs139400293	11:134,048,740	G/A	—	uncertain significance
rs146518105	11:134,048,770	C/T	—	uncertain significance
rs759492376	11:134,048,823	G/A	—	likely benign
rs750025141	11:134,051,009	T/C	—	uncertain significance
rs913854332	11:134,051,031	G/A	—	likely benign
rs868209407	11:134,051,034	G/A	—	uncertain significance
rs781574921	11:134,054,546	G/C	—	uncertain significance
rs148859668	11:134,054,583	G/A	—	likely benign
rs61752297	11:134,054,589	A/T	—	likely benign
rs761699157	11:134,054,641	A/T	—	uncertain significance
rs2497469763	11:134,054,808	G/C	—	uncertain significance
rs752931368	11:134,054,810	C/G	—	uncertain significance

Showing 100 of 177 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.