NCAPG
non-SMC condensin I complex subunit G
Summary
This gene encodes a subunit of the condensin complex, which is responsible for the condensation and stabilization of chromosomes during mitosis and meiosis. Phosphorylation of the encoded protein activates the condensin complex. There are pseudogenes for this gene on chromosomes 8 and 15. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Known Variants51 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs1410270071 | 4:17,812,774 | C/T | — | uncertain significance |
| rs1024810912 | 4:17,812,798 | G/T | — | uncertain significance |
| rs144588753 | 4:17,813,937 | A/G | — | uncertain significance |
| rs2474744098 | 4:17,813,965 | C/T | — | uncertain significance |
| rs2474746646 | 4:17,814,643 | T/A | — | uncertain significance |
| rs750006216 | 4:17,814,687 | A/T | — | uncertain significance |
| rs140348838 | 4:17,814,715 | T/C | — | uncertain significance |
| rs1476283933 | 4:17,814,718 | C/T | — | uncertain significance |
| rs1349962549 | 4:17,814,753 | T/C | — | uncertain significance |
| rs16895802 | 4:17,815,889 | C/G | regulatory region variant | — |
| rs774735569 | 4:17,816,520 | C/T | — | uncertain significance |
| rs1189574918 | 4:17,816,521 | G/A | — | uncertain significance |
| rs145849325 | 4:17,816,572 | T/C | — | uncertain significance |
| rs1402890533 | 4:17,816,949 | T/C | — | uncertain significance |
| rs747639864 | 4:17,818,950 | T/C | — | uncertain significance |
| rs141939992 | 4:17,818,960 | G/C | — | uncertain significance |
| rs150380263 | 4:17,819,027 | A/G | — | likely benign |
| rs138070486 | 4:17,819,584 | T/G | — | uncertain significance |
| rs765763382 | 4:17,819,617 | C/T | — | uncertain significance |
| rs745732498 | 4:17,819,671 | A/G | — | uncertain significance |
| rs11932971 | 4:17,823,902 | T/C | intron variant | — |
| rs748241009 | 4:17,824,625 | G/C | — | uncertain significance |
| rs753660180 | 4:17,825,272 | A/T | — | uncertain significance |
| rs368587786 | 4:17,826,616 | G/A | — | uncertain significance |
| rs376604108 | 4:17,826,642 | A/G | — | uncertain significance |
| rs776344403 | 4:17,827,039 | A/T | — | uncertain significance |
| rs139475495 | 4:17,827,108 | A/C | — | uncertain significance |
| rs1553850240 | 4:17,827,120 | A/G | — | uncertain significance |
| rs2474777242 | 4:17,829,919 | C/A | — | uncertain significance |
| rs148449510 | 4:17,829,958 | A/G | — | uncertain significance |
| rs758713662 | 4:17,829,968 | C/T | — | uncertain significance |
| rs1721852738 | 4:17,832,716 | A/C | — | uncertain significance |
| rs757238453 | 4:17,835,994 | G/A | — | uncertain significance |
| rs142788491 | 4:17,836,097 | C/T | — | uncertain significance |
| rs1722136259 | 4:17,838,860 | C/G | — | uncertain significance |
| rs779335060 | 4:17,838,913 | A/C | — | uncertain significance |
| rs371728981 | 4:17,838,944 | G/A | — | likely benign |
| rs750456309 | 4:17,839,347 | A/G | — | uncertain significance |
| rs2474797457 | 4:17,839,356 | G/C | — | uncertain significance |
| rs1264624573 | 4:17,841,369 | A/C | — | uncertain significance |
| rs901821416 | 4:17,841,375 | G/A | — | uncertain significance |
| rs150006629 | 4:17,841,412 | T/G | — | uncertain significance |
| rs1201388046 | 4:17,841,450 | A/G | — | uncertain significance |
| rs752155188 | 4:17,841,804 | G/T | — | uncertain significance |
| rs1383781119 | 4:17,842,257 | C/T | — | uncertain significance |
| rs146198577 | 4:17,842,280 | C/G | — | uncertain significance |
| rs1722489634 | 4:17,843,950 | G/C | — | uncertain significance |
| rs748965808 | 4:17,843,960 | G/A | — | uncertain significance |
| rs755265916 | 4:17,843,992 | G/A | — | uncertain significance |
| rs148031860 | 4:17,844,971 | C/T | — | uncertain significance |
| rs141707867 | 4:17,844,980 | G/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.