NEU4
neuraminidase 4
Summary
The protein encoded by this gene belongs to a family of glycohydrolytic enzymes, which remove terminal sialic acid residues from various sialo derivatives, such as glycoproteins, glycolipids, oligosaccharides, and gangliosides. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Nov 2009]
Known Variants57 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs62193087 | 2:242,749,988 | A/C | coding sequence variant | — |
| rs368612520 | 2:242,755,695 | G/A | — | likely benign |
| rs374918650 | 2:242,755,748 | C/T | — | uncertain significance |
| rs771531663 | 2:242,755,751 | G/A | — | uncertain significance |
| rs777106888 | 2:242,755,758 | C/T | — | uncertain significance |
| rs1700244036 | 2:242,755,784 | A/C | — | uncertain significance |
| rs368132672 | 2:242,755,806 | A/G | — | uncertain significance |
| rs758294570 | 2:242,756,104 | G/A | — | uncertain significance |
| rs149124108 | 2:242,756,152 | C/T | — | uncertain significance |
| rs772926572 | 2:242,756,237 | C/T | — | uncertain significance |
| rs756243325 | 2:242,756,255 | G/A | — | uncertain significance |
| rs1299357104 | 2:242,756,263 | T/C | — | uncertain significance |
| rs373747097 | 2:242,756,284 | G/A | — | uncertain significance |
| rs756400357 | 2:242,756,302 | G/T | — | uncertain significance |
| rs780252296 | 2:242,756,305 | C/T | — | uncertain significance |
| rs749431881 | 2:242,756,306 | G/A | — | uncertain significance |
| rs116702646 | 2:242,756,317 | G/A | — | likely benign |
| rs533165662 | 2:242,756,337 | C/T | — | likely benign |
| rs138327025 | 2:242,757,391 | G/A | — | uncertain significance |
| rs369447382 | 2:242,757,430 | C/T | — | uncertain significance |
| rs2469712504 | 2:242,757,433 | C/G | — | uncertain significance |
| rs771497956 | 2:242,757,445 | G/A | — | uncertain significance |
| rs750387336 | 2:242,757,470 | G/A | — | uncertain significance |
| rs141297986 | 2:242,757,494 | G/A | — | uncertain significance |
| rs961575217 | 2:242,757,499 | A/G | — | uncertain significance |
| rs370002261 | 2:242,757,547 | C/T | — | uncertain significance |
| rs1700331946 | 2:242,757,556 | G/A | — | uncertain significance |
| rs371140890 | 2:242,757,575 | G/A | — | uncertain significance |
| rs763731864 | 2:242,757,619 | G/A | — | uncertain significance |
| rs529825220 | 2:242,757,626 | T/C | — | uncertain significance |
| rs2469713850 | 2:242,757,692 | C/G | — | uncertain significance |
| rs895107049 | 2:242,757,713 | G/A | — | uncertain significance |
| rs745918303 | 2:242,757,759 | C/T | — | likely benign |
| rs371852061 | 2:242,757,778 | G/A | — | uncertain significance |
| rs200744809 | 2:242,757,794 | G/A | — | uncertain significance |
| rs773017188 | 2:242,757,881 | C/T | — | uncertain significance |
| rs762097709 | 2:242,757,910 | G/A | — | uncertain significance |
| rs1485213844 | 2:242,757,922 | A/G | — | uncertain significance |
| rs778698358 | 2:242,757,965 | C/T | — | uncertain significance |
| rs773540599 | 2:242,758,065 | C/G | — | uncertain significance |
| rs754004467 | 2:242,758,076 | G/A | — | uncertain significance |
| rs757037401 | 2:242,758,118 | C/T | — | uncertain significance |
| rs201343621 | 2:242,758,127 | C/T | — | uncertain significance |
| rs752802781 | 2:242,758,155 | C/G | — | uncertain significance |
| rs748822220 | 2:242,758,180 | G/A | — | uncertain significance |
| rs370021042 | 2:242,758,195 | G/A | — | uncertain significance |
| rs373540592 | 2:242,758,198 | C/T | — | uncertain significance |
| rs770027529 | 2:242,758,199 | C/T | — | uncertain significance |
| rs563096588 | 2:242,758,202 | C/T | — | uncertain significance |
| rs145897893 | 2:242,758,210 | G/T | — | uncertain significance |
| rs769967420 | 2:242,758,237 | G/C | — | uncertain significance |
| rs568289375 | 2:242,758,276 | T/C | — | uncertain significance |
| rs752175721 | 2:242,758,291 | C/T | — | uncertain significance |
| rs565670303 | 2:242,758,328 | C/T | — | uncertain significance |
| rs764606838 | 2:242,758,352 | G/A | — | uncertain significance |
| rs773119977 | 2:242,758,364 | G/T | — | uncertain significance |
| rs78353472 | 2:242,758,711 | C/T | 3 prime UTR variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.