NOBOX

NOBOX oogenesis homeobox

Summary

This homeobox gene encodes a transcription factor that is thought to play a role in oogenesis. In mice, it is essential for folliculogenesis and regulation of oocyte-specific genes. Defects in this gene result in premature ovarian failure type 5.[provided by RefSeq, May 2011]

Known Variants135 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs1208215	7:144,094,130	C/T	—	benign
rs57306880	7:144,094,256	A/C	—	benign
rs77802098	7:144,094,418	T/C	—	benign
rs2053899968	7:144,094,429	G/C	—	uncertain significance
rs1384557611	7:144,094,448	G/A	—	uncertain significance
rs1399859347	7:144,094,461	C/T	—	uncertain significance
rs116937127	7:144,094,471	T/C	—	uncertain significance
rs773878182	7:144,094,484	G/A	—	uncertain significance
rs762787878	7:144,094,502	G/T	—	uncertain significance
rs1213668924	7:144,094,508	G/A	—	uncertain significance
rs886062037	7:144,094,509	G/T	—	uncertain significance
rs1046041630	7:144,094,534	A/G	—	uncertain significance
rs146227301	7:144,094,553	G/A	—	benign
rs139083352	7:144,094,560	G/A	—	uncertain significance
rs1333215053	7:144,094,562	C/T	—	uncertain significance
rs2053901501	7:144,094,579	G/C	—	uncertain significance
rs115882574	7:144,094,583	G/A	—	conflicting classifications of pathogenicity
rs1474075353	7:144,094,606	C/A	—	uncertain significance
rs1208216	7:144,094,613	G/T	—	benign
rs149880524	7:144,094,642	G/T	—	benign
rs75574842	7:144,094,718	C/T	—	likely benign
rs1208217	7:144,094,783	A/G	—	benign
rs142147025	7:144,095,357	C/T	—	likely benign
rs749434230	7:144,095,364	C/T	—	uncertain significance
rs1332207318	7:144,095,390	G/A	—	uncertain significance
rs886062038	7:144,095,398	A/C	—	uncertain significance
rs1021125205	7:144,095,434	C/T	—	uncertain significance
rs371874278	7:144,095,440	G/A	—	benign
rs374879171	7:144,095,451	G/A	—	conflicting classifications of pathogenicity
rs572684632	7:144,095,458	C/T	—	uncertain significance
rs991408724	7:144,095,490	C/T	—	likely benign
rs370203452	7:144,095,500	G/A	—	uncertain significance
rs1335292601	7:144,095,557	G/A	—	uncertain significance
rs1009827355	7:144,095,586	C/G	—	uncertain significance
rs2699503	7:144,095,600	A/G	—	benign
rs531662858	7:144,095,603	G/A	—	conflicting classifications of pathogenicity
rs559175226	7:144,095,642	G/C	—	uncertain significance
rs1203231695	7:144,095,662	G/C	—	uncertain significance
rs762648490	7:144,095,666	G/T	—	conflicting classifications of pathogenicity
rs11979528	7:144,095,730	C/T	—	benign
rs2699502	7:144,095,880	T/C	—	benign
rs752775856	7:144,096,029	C/T	—	uncertain significance
rs376169208	7:144,096,030	G/A	—	likely benign
rs758913213	7:144,096,038	C/T	—	uncertain significance
rs376168456	7:144,096,062	A/G	—	uncertain significance
rs535798283	7:144,096,064	G/A	—	uncertain significance
rs554506207	7:144,096,065	G/C	—	uncertain significance
rs2525702	7:144,096,068	C/T	—	benign
rs1006463439	7:144,096,072	C/G	—	likely pathogenic
rs1467151739	7:144,096,081	G/T	—	uncertain significance
rs112190116	7:144,096,158	C/T	—	benign
rs776455519	7:144,096,175	G/A	—	uncertain significance
rs763087298	7:144,096,176	G/A	—	uncertain significance
rs767702371	7:144,096,190	G/C	—	uncertain significance
rs371673500	7:144,096,194	G/A	—	uncertain significance
rs780566386	7:144,096,205	C/T	—	uncertain significance
rs1476085935	7:144,096,214	C/A	—	likely pathogenic
rs576556766	7:144,096,241	G/C	—	uncertain significance
rs746771890	7:144,096,262	A/T	—	uncertain significance
rs776609191	7:144,096,269	G/A	—	uncertain significance
rs11769787	7:144,096,456	C/T	—	benign
rs748810300	7:144,096,508	G/A	—	uncertain significance
rs568492478	7:144,096,531	G/A	—	likely pathogenic
rs11769847	7:144,096,598	C/T	—	benign
rs185566002	7:144,096,772	C/T	intron variant	—
rs757388	7:144,096,839	A/G	—	benign
rs189306575	7:144,096,892	T/G	—	uncertain significance
rs199538689	7:144,096,925	C/T	—	likely benign
rs1218620893	7:144,096,926	G/A	—	likely pathogenic
rs754804125	7:144,096,938	G/A	—	uncertain significance
rs201947677	7:144,096,940	C/T	missense variant	pathogenic
rs193303104	7:144,096,956	C/A	missense variant	pathogenic
rs767110478	7:144,096,966	G/T	—	uncertain significance
rs765059051	7:144,097,216	G/A	—	likely benign
rs533330364	7:144,097,219	C/T	—	uncertain significance
rs193303103	7:144,097,225	C/G	missense variant	pathogenic
rs750447943	7:144,097,235	C/T	—	uncertain significance
rs372222051	7:144,097,262	C/T	—	uncertain significance
rs760223261	7:144,097,273	G/A	—	uncertain significance
rs753930313	7:144,097,327	G/A	—	uncertain significance
rs200423745	7:144,097,342	C/T	—	uncertain significance
rs193303102	7:144,097,343	G/A	stop gained	pathogenic
rs747497042	7:144,097,355	T/C	—	uncertain significance
rs1329086880	7:144,097,382	T/C	—	uncertain significance
rs1029551934	7:144,098,144	C/T	—	uncertain significance
rs774063334	7:144,098,189	G/A	—	uncertain significance
rs2128861658	7:144,098,192	G/A	—	uncertain significance
rs376598018	7:144,098,241	G/A	—	uncertain significance
rs760675411	7:144,098,280	A/G	—	uncertain significance
rs762139523	7:144,098,304	G/A	—	uncertain significance
rs750862438	7:144,098,324	G/A	—	uncertain significance
rs374655849	7:144,098,332	T/A	—	likely benign
rs372071820	7:144,098,355	T/C	—	uncertain significance
rs1428500486	7:144,098,370	T/C	—	uncertain significance
rs201423277	7:144,098,419	T/C	—	likely benign
rs754310626	7:144,098,444	G/A	—	uncertain significance
rs558507338	7:144,098,495	C/T	—	uncertain significance
rs372165690	7:144,098,496	G/C	—	likely benign
rs201806397	7:144,098,529	C/T	—	benign
rs2486118677	7:144,098,567	C/T	—	uncertain significance

Showing 100 of 135 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.