NPR3

natriuretic peptide receptor 3

Summary

This gene encodes one of three natriuretic peptide receptors. Natriutetic peptides are small peptides which regulate blood volume and pressure, pulmonary hypertension, and cardiac function as well as some metabolic and growth processes. The product of this gene encodes a natriuretic peptide receptor responsible for clearing circulating and extracellular natriuretic peptides through endocytosis of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]

Known Variants185 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs1458051	5:32,689,472	G/T	—	—
rs6450922	5:32,689,718	C/A	—	—
rs7729447	5:32,689,773	G/A	intron variant	—
rs55665822	5:32,705,431	A/G	intron variant	—
rs55738139	5:32,705,586	C/G	—	—
rs28513089	5:32,710,761	G/A	—	benign
rs572035979	5:32,710,786	G/A	—	benign
rs9716700	5:32,711,633	A/C	—	benign
rs116204726	5:32,711,877	G/C	—	benign
rs562074715	5:32,711,890	C/G	—	uncertain significance
rs752039844	5:32,711,912	C/T	—	likely benign
rs1170453410	5:32,711,915	G/A	—	likely benign
rs1561074170	5:32,711,925	C/G	—	uncertain significance
rs979108655	5:32,711,933	G/C	—	uncertain significance
rs1252696187	5:32,711,936	G/T	—	likely benign
rs1479414238	5:32,711,939	G/C	—	uncertain significance
rs1031989391	5:32,711,945	C/G	—	likely benign
rs1373301621	5:32,711,946	G/A	—	uncertain significance
rs957860113	5:32,711,954	C/T	—	likely benign
rs999782749	5:32,711,973	G/A	—	uncertain significance
rs1738259169	5:32,711,983	G/A	—	uncertain significance
rs1392690210	5:32,711,990	G/A	—	likely benign
rs1301392375	5:32,712,008	C/G	—	likely benign
rs1738264446	5:32,712,028	C/G	—	uncertain significance
rs749467577	5:32,712,039	A/G	—	uncertain significance
rs1460036658	5:32,712,042	G/C	—	uncertain significance
rs1474213281	5:32,712,065	G/C	—	uncertain significance
rs2478213513	5:32,712,078	T/C	—	likely benign
rs1325596990	5:32,712,100	G/A	—	uncertain significance
rs6859964	5:32,712,119	T/C	—	benign
rs1458329208	5:32,712,149	G/C	—	likely benign
rs374859010	5:32,712,154	G/T	—	uncertain significance
rs756559284	5:32,712,156	C/T	—	uncertain significance
rs745984932	5:32,712,167	G/A	—	likely benign
rs772129919	5:32,712,169	G/A	—	uncertain significance
rs2111840861	5:32,712,174	C/G	—	uncertain significance
rs1561074830	5:32,712,191	C/T	—	likely benign
rs374236891	5:32,712,212	C/T	—	likely benign
rs769527811	5:32,712,236	C/A	—	uncertain significance
rs1263411940	5:32,712,248	G/A	—	likely benign
rs1020773035	5:32,712,264	C/G	—	uncertain significance
rs1202238772	5:32,712,269	C/T	—	likely benign
rs754276633	5:32,712,299	A/G	—	likely benign
rs1433125500	5:32,712,324	T/C	—	likely pathogenic
rs2478215379	5:32,712,329	C/T	—	likely benign
rs758483759	5:32,712,350	G/A	—	likely benign
rs1228982969	5:32,712,398	G/T	—	likely benign
rs776997035	5:32,712,415	C/A	—	uncertain significance
rs2111842185	5:32,712,432	A/T	—	uncertain significance
rs781249323	5:32,712,465	C/T	—	uncertain significance
rs536801135	5:32,712,485	A/G	—	likely benign
rs891871524	5:32,712,508	T/A	—	uncertain significance
rs377062036	5:32,712,539	G/A	—	likely benign
rs770169526	5:32,712,565	G/A	—	uncertain significance
rs202144521	5:32,712,570	C/T	—	uncertain significance
rs1279843711	5:32,712,574	C/A	—	uncertain significance
rs763277450	5:32,712,575	G/A	—	likely benign
rs767430720	5:32,712,594	G/C	—	uncertain significance
rs2478217648	5:32,712,625	T/C	—	uncertain significance
rs2111843383	5:32,712,642	A/G	—	uncertain significance
rs746508357	5:32,712,645	G/C	—	uncertain significance
rs2111843419	5:32,712,647	G/A	—	likely benign
rs377559221	5:32,712,659	G/C	—	likely benign
rs371043582	5:32,712,668	C/A	—	likely benign
rs771228213	5:32,712,669	C/G	—	likely benign
rs1334706432	5:32,712,671	G/C	—	likely benign
rs77559951	5:32,712,674	C/T	—	benign
rs4867473	5:32,712,831	C/T	—	benign
rs3792765	5:32,713,836	A/G	regulatory region variant	—
rs1421811	5:32,714,270	C/T	—	—
rs2194178	5:32,718,044	C/T	intron variant	—
rs6889608	5:32,719,693	C/T	intron variant	—
rs113811158	5:32,721,116	G/A	—	—
rs374865702	5:32,724,794	C/T	—	likely benign
rs1269598391	5:32,724,800	C/T	—	likely benign
rs766009777	5:32,724,804	T/C	—	uncertain significance
rs186814909	5:32,724,806	G/T	—	conflicting classifications of pathogenicity
rs969206323	5:32,724,823	C/T	—	likely benign
rs775585104	5:32,724,837	G/A	—	uncertain significance
rs933468549	5:32,724,854	G/A	—	uncertain significance
rs374966067	5:32,724,855	C/T	—	uncertain significance
rs139065863	5:32,724,856	G/A	—	benign
rs374205048	5:32,724,886	C/T	—	likely benign
rs767132770	5:32,724,887	G/A	—	uncertain significance
rs1316577485	5:32,724,922	C/A	—	likely benign
rs200820724	5:32,724,942	C/A	—	benign
rs1147224	5:32,725,072	T/C	—	benign
rs700923	5:32,734,868	A/T	—	—
rs55871801	5:32,738,758	A/G	—	benign
rs2292025	5:32,738,886	G/A	—	benign
rs2292026	5:32,738,891	C/T	—	benign
rs372211082	5:32,738,960	T/C	—	likely benign
rs767222632	5:32,738,993	G/A	—	uncertain significance
rs750920406	5:32,739,011	G/A	—	uncertain significance
rs765541392	5:32,739,028	G/A	—	likely benign
rs151246481	5:32,739,121	C/T	—	likely benign
rs752059527	5:32,739,137	G/A	—	conflicting classifications of pathogenicity
rs201661872	5:32,739,143	G/A	—	likely benign
rs817898	5:32,739,289	G/T	—	benign
rs79938890	5:32,739,291	T/G	—	benign

Showing 100 of 185 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.