NRROS
negative regulator of reactive oxygen species
Summary
Enables transforming growth factor beta binding activity. Predicted to be involved in several processes, including microglia development; sequestering of TGFbeta in extracellular matrix; and transforming growth factor beta receptor signaling pathway. Located in cell surface. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants59 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs7636493 | 3:196,367,930 | G/A | intron variant | — |
| rs189974384 | 3:196,373,698 | A/G | intron variant | — |
| rs1737495759 | 3:196,381,439 | T/C | — | pathogenic |
| rs763103757 | 3:196,381,475 | G/A | — | uncertain significance |
| rs151257083 | 3:196,381,480 | G/A | — | uncertain significance |
| rs199961460 | 3:196,386,619 | G/A | — | uncertain significance |
| rs145529409 | 3:196,386,648 | G/A | — | uncertain significance |
| rs369864683 | 3:196,386,688 | C/A | — | uncertain significance |
| rs140967612 | 3:196,386,693 | G/A | — | conflicting classifications of pathogenicity |
| rs2108643149 | 3:196,386,699 | T/C | — | pathogenic |
| rs372524520 | 3:196,386,794 | G/C | — | uncertain significance |
| rs1464030780 | 3:196,386,800 | A/G | — | uncertain significance |
| rs1405858256 | 3:196,386,806 | C/T | — | uncertain significance |
| rs1324029062 | 3:196,386,824 | C/T | — | pathogenic |
| rs866758642 | 3:196,386,836 | C/T | — | uncertain significance |
| rs1737628442 | 3:196,386,871 | G/T | — | uncertain significance |
| rs1287408109 | 3:196,386,876 | A/C | — | uncertain significance |
| rs1737630473 | 3:196,386,935 | G/C | — | uncertain significance |
| rs1798631 | 3:196,386,964 | G/C | — | benign |
| rs61741938 | 3:196,386,965 | C/A | — | uncertain significance |
| rs140233771 | 3:196,387,058 | C/A | — | likely benign |
| rs751430332 | 3:196,387,064 | C/T | — | uncertain significance |
| rs111822102 | 3:196,387,121 | G/A | — | likely benign |
| rs757569746 | 3:196,387,211 | G/A | — | uncertain significance |
| rs2474180806 | 3:196,387,233 | G/A | — | likely pathogenic |
| rs2474180813 | 3:196,387,235 | T/A | — | uncertain significance |
| rs947349147 | 3:196,387,251 | G/C | — | uncertain significance |
| rs1165654458 | 3:196,387,289 | C/T | — | uncertain significance |
| rs149789251 | 3:196,387,309 | C/G | — | uncertain significance |
| rs1737645663 | 3:196,387,355 | G/A | — | uncertain significance |
| rs773554340 | 3:196,387,377 | G/A | — | uncertain significance |
| rs756100175 | 3:196,387,569 | C/T | — | uncertain significance |
| rs62636590 | 3:196,387,607 | A/C | — | uncertain significance |
| rs769570043 | 3:196,387,623 | G/A | — | uncertain significance |
| rs1239560651 | 3:196,387,631 | G/T | — | likely pathogenic |
| rs775822148 | 3:196,387,638 | C/T | — | uncertain significance |
| rs150316796 | 3:196,387,697 | C/G | — | uncertain significance |
| rs137985437 | 3:196,387,698 | C/T | — | uncertain significance |
| rs2108643995 | 3:196,387,736 | A/C | — | uncertain significance |
| rs2474181806 | 3:196,387,753 | G/T | — | uncertain significance |
| rs1212953079 | 3:196,387,821 | A/G | — | uncertain significance |
| rs141522978 | 3:196,387,939 | G/A | — | likely benign |
| rs773696780 | 3:196,387,946 | C/G | — | uncertain significance |
| rs778254745 | 3:196,387,977 | C/T | — | uncertain significance |
| rs749997451 | 3:196,387,979 | T/C | — | conflicting classifications of pathogenicity |
| rs775861475 | 3:196,388,046 | C/T | — | uncertain significance |
| rs200884430 | 3:196,388,145 | C/T | — | uncertain significance |
| rs201402973 | 3:196,388,160 | C/T | — | uncertain significance |
| rs1737673573 | 3:196,388,180 | G/T | — | uncertain significance |
| rs199580062 | 3:196,388,262 | C/G | — | uncertain significance |
| rs148864806 | 3:196,388,274 | G/A | — | uncertain significance |
| rs1737677036 | 3:196,388,291 | C/T | — | pathogenic |
| rs147587398 | 3:196,388,349 | C/T | — | uncertain significance |
| rs1560057330 | 3:196,388,357 | G/A | — | uncertain significance |
| rs78670696 | 3:196,388,402 | G/T | — | likely benign |
| rs62636584 | 3:196,388,416 | C/T | — | benign |
| rs756349236 | 3:196,388,417 | G/A | — | uncertain significance |
| rs142890318 | 3:196,388,474 | G/A | — | likely benign |
| rs140011218 | 3:196,388,568 | G/A | — | likely benign |
Gene information from NCBI Gene. Variant classifications from ClinVar.