OGN
osteoglycin
Summary
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded protein induces ectopic bone formation in conjunction with transforming growth factor beta and may regulate osteoblast differentiation. High expression of the encoded protein may be associated with elevated heart left ventricular mass. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Known Variants11 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs140783624 | 9:95,148,009 | G/A | — | uncertain significance |
| rs1300279984 | 9:95,148,544 | T/C | — | uncertain significance |
| rs1157668732 | 9:95,155,398 | T/G | — | uncertain significance |
| rs1842757175 | 9:95,155,431 | C/T | — | uncertain significance |
| rs767502674 | 9:95,155,443 | G/C | — | uncertain significance |
| rs777898257 | 9:95,156,101 | A/G | — | — |
| rs777793451 | 9:95,163,400 | G/A | — | uncertain significance |
| rs146105137 | 9:95,163,409 | G/A | — | uncertain significance |
| rs768637841 | 9:95,163,441 | A/T | — | uncertain significance |
| rs762694663 | 9:95,165,607 | C/T | — | uncertain significance |
| rs143188159 | 9:95,165,611 | A/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.