ONECUT2
one cut homeobox 2
Summary
This gene encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. The protein binds to specific DNA sequences and stimulates expression of target genes, including genes involved in melanocyte and hepatocyte differentiation. [provided by RefSeq, Jul 2008]
Known Variants35 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs771378400 | 18:55,102,967 | G/A | — | uncertain significance |
| rs369785174 | 18:55,103,006 | A/G | — | uncertain significance |
| rs751553928 | 18:55,103,007 | T/C | — | uncertain significance |
| rs781095849 | 18:55,103,013 | C/G | — | uncertain significance |
| rs778121953 | 18:55,103,048 | G/T | — | uncertain significance |
| rs775311962 | 18:55,103,063 | G/T | — | uncertain significance |
| rs1404257944 | 18:55,103,064 | G/A | — | uncertain significance |
| rs201085296 | 18:55,103,078 | G/A | — | likely benign |
| rs1039196306 | 18:55,103,092 | C/G | — | likely benign |
| rs1486605675 | 18:55,103,109 | G/T | — | uncertain significance |
| rs1315311088 | 18:55,103,118 | A/G | — | uncertain significance |
| rs1232029502 | 18:55,103,122 | G/T | — | uncertain significance |
| rs927961875 | 18:55,103,126 | G/A | — | uncertain significance |
| rs940506922 | 18:55,103,166 | G/T | — | uncertain significance |
| rs2511467243 | 18:55,103,183 | C/T | — | uncertain significance |
| rs115372949 | 18:55,103,308 | G/A | — | benign |
| rs200319925 | 18:55,103,439 | C/G | — | uncertain significance |
| rs186386413 | 18:55,103,500 | C/G | — | uncertain significance |
| rs566844091 | 18:55,103,519 | G/A | — | uncertain significance |
| rs2511467665 | 18:55,103,525 | G/A | — | uncertain significance |
| rs368237468 | 18:55,103,551 | G/T | — | uncertain significance |
| rs2511467737 | 18:55,103,586 | C/T | — | uncertain significance |
| rs777194115 | 18:55,103,624 | C/G | — | uncertain significance |
| rs758793701 | 18:55,103,630 | G/A | — | uncertain significance |
| rs1598927062 | 18:55,103,652 | G/T | — | uncertain significance |
| rs747973204 | 18:55,103,737 | C/G | — | uncertain significance |
| rs1275256348 | 18:55,103,760 | C/A | — | uncertain significance |
| rs541827118 | 18:55,103,865 | C/T | — | uncertain significance |
| rs772738424 | 18:55,103,868 | T/C | — | uncertain significance |
| rs1297497235 | 18:55,103,876 | C/T | — | uncertain significance |
| rs764014713 | 18:55,103,888 | C/T | — | uncertain significance |
| rs615180 | 18:55,127,435 | G/A | intron variant | — |
| rs766718085 | 18:55,143,677 | C/T | — | uncertain significance |
| rs770906620 | 18:55,143,710 | A/T | — | uncertain significance |
| rs8099788 | 18:55,143,940 | G/A | — | benign |
Gene information from NCBI Gene. Variant classifications from ClinVar.