OR2J2
olfactory receptor family 2 subfamily J member 2
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Known Variants17 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs3130740 | 6:29,138,949 | A/G | upstream gene variant | — |
| rs537704908 | 6:29,141,456 | T/C | — | uncertain significance |
| rs774525822 | 6:29,141,459 | T/C | — | uncertain significance |
| rs199886529 | 6:29,141,479 | C/G | — | uncertain significance |
| rs772463705 | 6:29,141,542 | C/G | — | uncertain significance |
| rs766312489 | 6:29,141,630 | G/C | — | uncertain significance |
| rs369003322 | 6:29,141,671 | C/T | — | likely benign |
| rs780457511 | 6:29,141,831 | G/A | — | uncertain significance |
| rs375969093 | 6:29,141,981 | G/A | — | uncertain significance |
| rs1337351768 | 6:29,142,026 | C/G | — | uncertain significance |
| rs370809520 | 6:29,142,096 | C/G | — | likely benign |
| rs1401030509 | 6:29,142,122 | A/G | — | uncertain significance |
| rs777093037 | 6:29,142,140 | G/A | — | uncertain significance |
| rs199819597 | 6:29,142,182 | T/C | — | uncertain significance |
| rs1334658940 | 6:29,142,221 | A/C | — | uncertain significance |
| rs368672235 | 6:29,142,263 | C/T | — | uncertain significance |
| rs28757219 | 6:29,143,451 | A/T | downstream gene variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.