OSBPL10
oxysterol binding protein like 10
Summary
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
Known Variants52 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs367862538 | 3:31,705,587 | T/C | — | uncertain significance |
| rs1047992404 | 3:31,705,606 | G/A | — | uncertain significance |
| rs1424892493 | 3:31,705,612 | T/A | — | likely benign |
| rs375455808 | 3:31,705,657 | G/A | — | uncertain significance |
| rs780374078 | 3:31,705,693 | G/A | — | uncertain significance |
| rs1434838563 | 3:31,710,141 | C/G | — | uncertain significance |
| rs1265358608 | 3:31,710,142 | C/G | — | uncertain significance |
| rs758584031 | 3:31,710,198 | T/C | — | uncertain significance |
| rs374288288 | 3:31,710,200 | G/A | — | uncertain significance |
| rs1575463274 | 3:31,710,255 | A/G | — | uncertain significance |
| rs1376592074 | 3:31,712,334 | G/A | — | uncertain significance |
| rs773748652 | 3:31,712,371 | C/T | — | uncertain significance |
| rs199691636 | 3:31,712,392 | A/T | — | uncertain significance |
| rs2470834037 | 3:31,712,446 | C/T | — | uncertain significance |
| rs139317397 | 3:31,725,213 | C/T | — | likely benign |
| rs142316297 | 3:31,725,300 | C/T | — | uncertain significance |
| rs748353940 | 3:31,725,303 | C/T | — | uncertain significance |
| rs140782910 | 3:31,725,315 | C/T | — | uncertain significance |
| rs188713175 | 3:31,725,335 | C/T | — | likely benign |
| rs1169469753 | 3:31,725,378 | C/T | — | uncertain significance |
| rs138075476 | 3:31,725,435 | C/T | — | uncertain significance |
| rs889239649 | 3:31,725,493 | C/G | — | uncertain significance |
| rs760766000 | 3:31,725,495 | C/T | — | uncertain significance |
| rs754059421 | 3:31,725,513 | C/T | — | uncertain significance |
| rs369118257 | 3:31,743,906 | C/T | — | likely benign |
| rs373262269 | 3:31,743,980 | C/G | — | uncertain significance |
| rs762811753 | 3:31,774,871 | G/A | — | uncertain significance |
| rs756460016 | 3:31,774,891 | C/A | — | uncertain significance |
| rs768323621 | 3:31,789,461 | T/C | — | likely benign |
| rs200674528 | 3:31,789,537 | T/C | — | uncertain significance |
| rs2290532 | 3:31,789,582 | T/A | missense variant | — |
| rs759687989 | 3:31,789,606 | T/G | — | uncertain significance |
| rs1902341 | 3:31,795,570 | C/A | — | — |
| rs55995766 | 3:31,846,542 | G/A | — | — |
| rs2470665750 | 3:31,871,560 | T/C | — | uncertain significance |
| rs751308846 | 3:31,871,582 | C/T | — | uncertain significance |
| rs74377137 | 3:31,871,592 | C/T | — | likely benign |
| rs200394671 | 3:31,871,606 | T/C | — | uncertain significance |
| rs781373263 | 3:31,871,707 | C/T | — | uncertain significance |
| rs150619242 | 3:31,917,936 | T/C | — | uncertain significance |
| rs753942743 | 3:31,917,998 | T/C | — | uncertain significance |
| rs1695503589 | 3:31,921,271 | C/G | — | uncertain significance |
| rs1248624463 | 3:31,921,274 | A/T | — | uncertain significance |
| rs6810295 | 3:31,967,967 | G/A | intron variant | — |
| rs12630931 | 3:31,981,767 | T/C | intron variant | — |
| rs552804778 | 3:31,987,368 | C/T | — | — |
| rs759797326 | 3:32,022,443 | G/A | — | uncertain significance |
| rs750430465 | 3:32,022,473 | C/G | — | uncertain significance |
| rs554412374 | 3:32,022,539 | C/A | — | uncertain significance |
| rs1339542837 | 3:32,022,608 | T/C | — | uncertain significance |
| rs960682157 | 3:32,022,630 | G/T | — | uncertain significance |
| rs143143113 | 3:32,037,175 | G/A | downstream gene variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.