PABPN1L
PABPN1 like, cytoplasmic
Summary
Predicted to enable poly(A) binding activity. Predicted to be involved in nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay. Predicted to act upstream of or within maternal-to-zygotic transition of gene expression; negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process; and negative regulation of protein ubiquitination. Predicted to be located in cytoplasm. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants35 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs117427564 | 16:88,929,627 | G/A | — | — |
| rs1169187242 | 16:88,930,184 | G/T | — | uncertain significance |
| rs368865027 | 16:88,930,198 | C/T | — | uncertain significance |
| rs1436049419 | 16:88,930,201 | G/T | — | uncertain significance |
| rs758401342 | 16:88,930,705 | G/C | — | likely benign |
| rs906370462 | 16:88,930,721 | G/A | — | uncertain significance |
| rs751579358 | 16:88,930,724 | G/A | — | uncertain significance |
| rs182596572 | 16:88,930,739 | C/T | — | uncertain significance |
| rs768168928 | 16:88,930,742 | G/A | — | uncertain significance |
| rs770312100 | 16:88,930,769 | T/C | — | uncertain significance |
| rs775977916 | 16:88,930,774 | C/G | — | uncertain significance |
| rs374867060 | 16:88,930,780 | G/A | — | uncertain significance |
| rs764218577 | 16:88,930,781 | G/A | — | uncertain significance |
| rs752321965 | 16:88,931,271 | C/T | — | uncertain significance |
| rs758035491 | 16:88,931,272 | G/C | — | uncertain significance |
| rs532230190 | 16:88,931,305 | C/T | — | uncertain significance |
| rs780812870 | 16:88,931,314 | C/T | — | uncertain significance |
| rs1352826201 | 16:88,931,322 | T/G | — | uncertain significance |
| rs377167731 | 16:88,931,328 | G/A | — | uncertain significance |
| rs375109044 | 16:88,931,445 | G/C | — | uncertain significance |
| rs756250744 | 16:88,931,451 | T/A | — | uncertain significance |
| rs1450802782 | 16:88,931,472 | C/T | — | uncertain significance |
| rs141666111 | 16:88,931,515 | C/T | — | uncertain significance |
| rs760201583 | 16:88,931,518 | C/T | — | uncertain significance |
| rs373190927 | 16:88,931,990 | C/G | — | uncertain significance |
| rs537995208 | 16:88,932,017 | G/A | — | uncertain significance |
| rs1428455188 | 16:88,932,265 | C/T | — | uncertain significance |
| rs770096468 | 16:88,932,268 | C/T | — | uncertain significance |
| rs774492275 | 16:88,932,277 | G/C | — | uncertain significance |
| rs1011502527 | 16:88,932,280 | C/T | — | uncertain significance |
| rs922928988 | 16:88,932,282 | C/G | — | uncertain significance |
| rs1313195608 | 16:88,932,314 | C/T | — | uncertain significance |
| rs575921419 | 16:88,932,783 | C/G | — | uncertain significance |
| rs905253839 | 16:88,932,833 | T/A | — | uncertain significance |
| rs181483773 | 16:88,933,228 | T/A | downstream gene variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.