PARD3

par-3 family cell polarity regulator

Summary

This gene encodes a member of the PARD protein family. PARD family members interact with other PARD family members and other proteins; they affect asymmetrical cell division and direct polarized cell growth. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011]

Known Variants128 total

rsidPosition (GRCh37)AllelesClassClinVar
rs4127609010:34,400,093A/G—benign
rs76673824210:34,400,116C/G—uncertain significance
rs14927846110:34,400,128G/T—uncertain significance
rs14443375410:34,400,149G/A—uncertain significance
rs20076024510:34,400,182C/T—uncertain significance
rs76460268310:34,400,255C/G—uncertain significance
rs54981488910:34,400,340G/A—likely benign
rs20177404110:34,400,366C/T—uncertain significance
rs14484423210:34,400,403C/T—likely benign
rs75725902310:34,400,423C/T—risk factor
rs37140135710:34,400,434G/T—uncertain significance
rs37428168410:34,400,460G/A—likely benign
rs37761317110:34,400,467G/A—uncertain significance
rs76543637710:34,408,542G/A—uncertain significance
rs194687444910:34,408,560G/C—uncertain significance
rs104292960510:34,408,598C/T—uncertain significance
rs14577409610:34,408,623C/T—uncertain significance
rs1100965110:34,408,636T/C—benign
rs6173556810:34,408,649G/A—benign
rs77649265310:34,408,655G/A—uncertain significance
rs77286287410:34,408,666C/T—likely benign
rs6173557110:34,420,394G/C—likely benign
rs5679693210:34,442,885G/Aintron variant—
rs224837510:34,452,072C/T——
rs166062210:34,456,509C/G——
rs14882667010:34,463,041C/Aintron variant—
rs61429910:34,465,205C/Tintron variant—
rs20078000510:34,558,577G/A—likely benign
rs75520299410:34,558,612C/T—uncertain significance
rs77620109810:34,558,649T/C—uncertain significance
rs20183120310:34,558,660C/T—uncertain significance
rs74837477810:34,558,696C/A—uncertain significance
rs13909828510:34,558,712C/T—likely benign
rs14945552010:34,558,715C/T—benign
rs20207823810:34,558,722C/T—uncertain significance
rs20136001310:34,558,795C/T—uncertain significance
rs375845810:34,558,808C/G—likely benign
rs91007751510:34,558,823G/C—uncertain significance
rs1076397610:34,564,292G/Aintron variant—
rs64116210:34,566,920G/Aintron variant—
rs14743609910:34,573,069T/C—uncertain significance
rs15126285210:34,573,090C/G—uncertain significance
rs75535582310:34,573,125T/C—uncertain significance
rs74859531810:34,573,133C/T—uncertain significance
rs37425857310:34,573,135G/A—uncertain significance
rs200765510:34,586,689T/Gregulatory region variant—
rs77127696610:34,606,066C/G—uncertain significance
rs14655478010:34,606,071T/C—uncertain significance
rs14431732810:34,606,124A/G—benign
rs75122613210:34,606,139T/C—likely benign
rs20013031210:34,606,158T/C—likely benign
rs37729003610:34,606,232C/T—likely benign
rs104014835810:34,606,255T/G—uncertain significance
rs14897071210:34,606,262T/C—likely benign
rs14378643810:34,620,047G/A—uncertain significance
rs1693532610:34,620,077G/A—benign
rs14713669410:34,620,100G/A—likely benign
rs75516234810:34,620,148C/T—likely benign
rs78146146210:34,620,149G/Tmissense variantpathogenic
rs378112810:34,620,220C/T—benign
rs77754057310:34,625,153A/C—uncertain significance
rs76292129710:34,625,160T/A—risk factor
rs5873185810:34,626,193T/C—benign
rs14852791210:34,626,323C/T—uncertain significance
rs11815323010:34,630,570C/T—benign
rs77445614410:34,630,605C/T—likely benign
rs111416735410:34,630,624T/C—pathogenic
rs6173556310:34,630,698A/T—benign
rs89196629110:34,630,742T/C—uncertain significance
rs76163606010:34,637,003A/G—uncertain significance
rs18575750710:34,637,050A/G—likely benign
rs99434634510:34,648,124C/T—uncertain significance
rs13829221810:34,648,130T/C—uncertain significance
rs20109831210:34,648,232C/T—uncertain significance
rs36863926710:34,649,069C/T—uncertain significance
rs77991799810:34,649,130A/G—uncertain significance
rs6173556410:34,649,134C/G—benign
rs6173556510:34,649,146G/C—benign
rs249534486810:34,649,169T/C—uncertain significance
rs249575475410:34,666,990T/C—uncertain significance
rs13955073510:34,671,513T/C—likely benign
rs77073364310:34,671,533G/A—uncertain significance
rs14176942710:34,671,584G/A—uncertain significance
rs249586950310:34,671,616A/G—likely benign
rs11507637010:34,671,617G/A—conflicting classifications of pathogenicity
rs14009871410:34,671,623A/G—likely benign
rs36989548310:34,671,626T/G—uncertain significance
rs20076903710:34,671,635G/A—uncertain significance
rs99706587110:34,671,711T/G—uncertain significance
rs20148453410:34,671,743T/C—uncertain significance
rs139421359810:34,671,783T/C—uncertain significance
rs19992344810:34,671,821C/T—uncertain significance
rs75841194110:34,671,833C/T—uncertain significance
rs54988735410:34,673,131A/C—likely benign
rs249625539410:34,688,261C/A—uncertain significance
rs77405574610:34,688,267C/G—uncertain significance
rs6262503210:34,688,273C/G—likely benign
rs249625663010:34,688,320T/C—likely benign
rs20103957410:34,690,784C/T—uncertain significance
rs76676091810:34,690,814C/T—uncertain significance

Showing 100 of 128 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.