PATL2
PAT1 homolog 2
Summary
Predicted to enable RNA binding activity. Predicted to be involved in P-body assembly; deadenylation-dependent decapping of nuclear-transcribed mRNA; and negative regulation of translation. Predicted to act upstream of or within negative regulation of cytoplasmic mRNA processing body assembly. Located in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants52 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs186338121 | 15:44,958,010 | A/T | — | uncertain significance |
| rs201470968 | 15:44,958,608 | T/G | — | uncertain significance |
| rs1044545 | 15:44,958,652 | T/C | — | benign |
| rs1595953056 | 15:44,958,673 | G/C | — | likely benign |
| rs2085412928 | 15:44,959,314 | G/A | — | uncertain significance |
| rs1385197699 | 15:44,959,349 | G/A | — | uncertain significance |
| rs1453668266 | 15:44,959,353 | C/T | — | uncertain significance |
| rs2505837677 | 15:44,959,356 | G/T | — | uncertain significance |
| rs775346086 | 15:44,959,374 | G/T | — | uncertain significance |
| rs760378079 | 15:44,960,557 | C/T | — | likely benign |
| rs2505852621 | 15:44,960,565 | G/A | — | uncertain significance |
| rs372636647 | 15:44,960,595 | G/A | — | likely benign |
| rs2505853884 | 15:44,960,629 | G/A | — | likely benign |
| rs1272591469 | 15:44,960,631 | G/A | — | uncertain significance |
| rs1042132112 | 15:44,960,665 | A/G | — | uncertain significance |
| rs1341424851 | 15:44,960,682 | T/C | — | pathogenic |
| rs1474577110 | 15:44,960,683 | G/T | — | uncertain significance |
| rs1555385717 | 15:44,961,176 | A/G | — | pathogenic |
| rs528374242 | 15:44,961,180 | G/C | — | uncertain significance |
| rs199627539 | 15:44,961,197 | C/T | — | uncertain significance |
| rs931510105 | 15:44,961,228 | C/T | — | uncertain significance |
| rs190933513 | 15:44,961,256 | G/C | — | likely benign |
| rs1397500378 | 15:44,961,294 | C/T | — | uncertain significance |
| rs1336958025 | 15:44,961,303 | C/G | — | uncertain significance |
| rs758350818 | 15:44,961,524 | C/T | — | uncertain significance |
| rs779813875 | 15:44,961,544 | T/C | — | uncertain significance |
| rs937496181 | 15:44,961,559 | G/A | — | uncertain significance |
| rs1011539285 | 15:44,961,589 | A/G | missense variant | uncertain significance |
| rs569729547 | 15:44,962,012 | C/T | missense variant | uncertain significance |
| rs2085575519 | 15:44,962,015 | C/T | — | uncertain significance |
| rs951044203 | 15:44,962,033 | G/A | — | uncertain significance |
| rs140098598 | 15:44,962,037 | C/T | — | benign |
| rs892789170 | 15:44,962,040 | C/T | — | uncertain significance |
| rs928887955 | 15:44,962,058 | C/T | — | uncertain significance |
| rs1351320025 | 15:44,962,067 | G/A | — | likely pathogenic |
| rs754039562 | 15:44,962,228 | T/G | — | uncertain significance |
| rs951076370 | 15:44,962,233 | C/T | — | conflicting classifications of pathogenicity |
| rs577616730 | 15:44,962,250 | G/A | — | likely benign |
| rs1361024832 | 15:44,964,221 | A/T | — | likely pathogenic |
| rs2505900199 | 15:44,964,296 | T/C | — | uncertain significance |
| rs1156737044 | 15:44,964,304 | A/C | — | likely pathogenic |
| rs752734259 | 15:44,964,312 | A/T | stop gained | pathogenic |
| rs185242322 | 15:44,964,318 | G/A | — | likely benign |
| rs548527219 | 15:44,964,623 | G/A | stop gained | pathogenic |
| rs1350038531 | 15:44,965,432 | C/G | — | likely pathogenic |
| rs770246020 | 15:44,965,450 | C/A | — | likely benign |
| rs1050285529 | 15:44,965,559 | G/C | — | uncertain significance |
| rs8026845 | 15:44,966,389 | T/C | — | benign |
| rs749598645 | 15:44,966,396 | G/A | — | likely benign |
| rs759128846 | 15:44,967,728 | C/T | — | uncertain significance |
| rs562812709 | 15:44,967,780 | G/C | — | likely benign |
| rs77918503 | 15:44,967,847 | A/G | — | benign |
Gene information from NCBI Gene. Variant classifications from ClinVar.