PIP
prolactin induced protein
Summary
Enables IgG binding activity; aspartic-type endopeptidase activity; and identical protein binding activity. Involved in several processes, including detection of chemical stimulus involved in sensory perception of bitter taste; negative regulation of T cell apoptotic process; and proteolysis. Located in extracellular space and nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants10 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs560996067 | 7:142,828,337 | G/A | — | — |
| rs199681727 | 7:142,829,274 | A/T | — | uncertain significance |
| rs147746570 | 7:142,829,295 | A/G | — | likely benign |
| rs747002680 | 7:142,832,289 | G/T | — | uncertain significance |
| rs112182232 | 7:142,832,341 | C/T | — | benign |
| rs560032421 | 7:142,832,384 | T/C | — | uncertain significance |
| rs2486641426 | 7:142,836,269 | C/G | — | uncertain significance |
| rs75076193 | 7:142,836,646 | C/T | — | benign |
| rs775533580 | 7:142,836,713 | T/C | — | likely benign |
| rs147384445 | 7:142,836,720 | C/A | — | benign |
Gene information from NCBI Gene. Variant classifications from ClinVar.