PKIB
cAMP-dependent protein kinase inhibitor beta
Summary
This gene encodes a member of the cAMP-dependent protein kinase inhibitor family. The encoded protein may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of this gene may play a role in prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Known Variants19 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs509596 | 6:122,799,541 | G/C | — | — |
| rs34157234 | 6:122,808,015 | G/T | intron variant | — |
| rs7767237 | 6:122,809,574 | C/G | intron variant | — |
| rs155465 | 6:122,832,172 | G/A | intron variant | — |
| rs129830 | 6:122,835,447 | C/G | — | — |
| rs197694 | 6:122,844,409 | C/G | — | — |
| rs197678 | 6:122,855,184 | A/T | — | — |
| rs372656572 | 6:122,859,209 | G/A | — | — |
| rs35524515 | 6:122,868,773 | G/T | intron variant | — |
| rs2021407 | 6:122,880,297 | C/T | intron variant | — |
| rs9388099 | 6:122,888,049 | C/G | — | — |
| rs10457437 | 6:122,979,479 | C/T | intron variant | — |
| rs78311405 | 6:123,038,971 | T/C | — | uncertain significance |
| rs201327015 | 6:123,039,060 | G/A | — | uncertain significance |
| rs1252180326 | 6:123,039,066 | T/G | — | uncertain significance |
| rs182893341 | 6:123,039,070 | A/G | — | uncertain significance |
| rs77659800 | 6:123,039,087 | G/A | — | uncertain significance |
| rs141912516 | 6:123,039,093 | C/G | — | uncertain significance |
| rs186699539 | 6:123,041,825 | A/G | intron variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.