PLA2G2E
phospholipase A2 group IIE
Summary
Enables calcium ion binding activity and calcium-dependent phospholipase A2 activity. Predicted to be involved in phosphatidylcholine metabolic process and phosphatidylglycerol metabolic process. Predicted to act upstream of or within low-density lipoprotein particle remodeling. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants14 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs958966462 | 1:20,246,874 | T/C | — | uncertain significance |
| rs2045805004 | 1:20,246,880 | G/A | — | uncertain significance |
| rs1474530851 | 1:20,246,901 | T/C | — | uncertain significance |
| rs559232898 | 1:20,248,806 | G/C | — | uncertain significance |
| rs1450420106 | 1:20,248,819 | G/C | — | uncertain significance |
| rs760306746 | 1:20,248,824 | G/A | — | uncertain significance |
| rs1226907475 | 1:20,248,887 | C/T | — | uncertain significance |
| rs769718316 | 1:20,249,111 | A/C | — | uncertain significance |
| rs140234785 | 1:20,249,203 | T/C | — | uncertain significance |
| rs1397149890 | 1:20,249,230 | T/G | — | uncertain significance |
| rs369084711 | 1:20,249,234 | C/T | — | uncertain significance |
| rs995211621 | 1:20,249,240 | C/G | — | uncertain significance |
| rs369817622 | 1:20,249,246 | C/T | — | uncertain significance |
| rs193024312 | 1:20,249,354 | G/A | intron variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.