POLR3C
RNA polymerase III subunit C
Summary
Enables single-stranded DNA binding activity. Involved in positive regulation of innate immune response and positive regulation of interferon-beta production. Located in nucleoplasm. Part of RNA polymerase III complex. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants31 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs2526233209 | 1:145,594,066 | A/T | — | uncertain significance |
| rs1553730406 | 1:145,594,088 | T/A | — | uncertain significance |
| rs150281840 | 1:145,595,144 | C/T | — | uncertain significance |
| rs2526217236 | 1:145,596,943 | C/A | — | uncertain significance |
| rs372221810 | 1:145,596,944 | A/G | — | uncertain significance |
| rs139697925 | 1:145,597,025 | C/T | — | likely benign |
| rs1553729266 | 1:145,597,052 | A/G | — | uncertain significance |
| rs9728345 | 1:145,597,417 | C/A | — | benign |
| rs782414994 | 1:145,598,295 | G/A | — | likely benign |
| rs782400288 | 1:145,601,527 | C/T | — | uncertain significance |
| rs587609843 | 1:145,601,552 | G/A | — | uncertain significance |
| rs1651526432 | 1:145,601,594 | A/C | — | uncertain significance |
| rs2526183718 | 1:145,601,752 | T/C | — | uncertain significance |
| rs2526183502 | 1:145,601,777 | C/G | — | uncertain significance |
| rs782234829 | 1:145,606,309 | G/C | — | uncertain significance |
| rs368282627 | 1:145,608,120 | G/A | — | uncertain significance |
| rs139560249 | 1:145,608,122 | T/G | — | likely benign |
| rs1295241905 | 1:145,608,135 | A/G | — | uncertain significance |
| rs144290770 | 1:145,608,146 | T/C | — | likely benign |
| rs781955549 | 1:145,608,164 | G/C | — | uncertain significance |
| rs200282639 | 1:145,608,221 | C/T | — | uncertain significance |
| rs587636314 | 1:145,608,509 | T/C | — | uncertain significance |
| rs587709859 | 1:145,608,539 | G/A | — | uncertain significance |
| rs115748902 | 1:145,608,556 | C/T | — | likely benign |
| rs377694831 | 1:145,608,574 | T/C | — | uncertain significance |
| rs782403713 | 1:145,608,598 | C/T | — | uncertain significance |
| rs2526132678 | 1:145,608,616 | C/G | — | uncertain significance |
| rs1553725761 | 1:145,608,617 | T/A | — | uncertain significance |
| rs587726704 | 1:145,609,245 | G/A | — | uncertain significance |
| rs782182340 | 1:145,609,266 | A/G | — | uncertain significance |
| rs116129062 | 1:145,609,619 | T/A | upstream gene variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.