POP5
POP5 ribonuclease P/MRP subunit
Summary
Enables ribonuclease P RNA binding activity. Contributes to ribonuclease P activity. Involved in tRNA 5'-leader removal. Located in nucleolus. Part of multimeric ribonuclease P complex and ribonuclease MRP complex. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants9 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs765742152 | 12:121,017,129 | T/C | — | uncertain significance |
| rs760154803 | 12:121,017,197 | T/C | — | uncertain significance |
| rs1040403223 | 12:121,017,613 | G/T | — | uncertain significance |
| rs762946962 | 12:121,017,679 | T/C | — | uncertain significance |
| rs200099424 | 12:121,018,964 | C/A | — | uncertain significance |
| rs2500809049 | 12:121,019,022 | C/T | — | uncertain significance |
| rs145609940 | 12:121,019,148 | G/C | — | uncertain significance |
| rs523522 | 12:121,020,250 | A/T | downstream gene variant | — |
| rs111593205 | 12:121,020,916 | T/G | upstream gene variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.