PPP6R3
protein phosphatase 6 regulatory subunit 3
Summary
Protein phosphatase regulatory subunits, such as SAPS3, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS3 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 [PubMed 16769727]).[supplied by OMIM, Nov 2010]
Known Variants50 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs78564655 | 11:68,233,806 | C/T | intron variant | — |
| rs139186781 | 11:68,240,648 | A/G | intron variant | — |
| rs190132318 | 11:68,243,304 | C/G | intron variant | — |
| rs73516862 | 11:68,245,648 | T/C | intron variant | — |
| rs12364620 | 11:68,252,123 | T/G | downstream gene variant | — |
| rs12274114 | 11:68,255,577 | A/C | downstream gene variant | — |
| rs12272917 | 11:68,263,370 | T/A | — | — |
| rs72936524 | 11:68,275,898 | G/T | — | — |
| rs17601605 | 11:68,286,865 | A/T | intron variant | — |
| rs57008984 | 11:68,295,903 | G/C | — | — |
| rs2099278291 | 11:68,305,265 | A/T | — | uncertain significance |
| rs140917558 | 11:68,305,316 | A/T | — | uncertain significance |
| rs748618569 | 11:68,312,318 | A/G | — | uncertain significance |
| rs779543631 | 11:68,312,415 | G/A | — | uncertain significance |
| rs768876542 | 11:68,315,577 | A/G | — | uncertain significance |
| rs1039365878 | 11:68,315,604 | A/G | — | uncertain significance |
| rs147458286 | 11:68,318,651 | A/T | — | uncertain significance |
| rs554062169 | 11:68,331,784 | A/G | — | uncertain significance |
| rs764314539 | 11:68,331,833 | A/G | — | uncertain significance |
| rs2509404529 | 11:68,331,877 | G/C | — | uncertain significance |
| rs2509405519 | 11:68,331,895 | C/T | — | uncertain significance |
| rs908176986 | 11:68,334,515 | G/C | — | uncertain significance |
| rs2509581728 | 11:68,334,606 | T/C | — | uncertain significance |
| rs772874803 | 11:68,334,616 | T/G | — | uncertain significance |
| rs770022844 | 11:68,337,219 | A/G | — | uncertain significance |
| rs765880615 | 11:68,337,280 | T/C | — | uncertain significance |
| rs1173036290 | 11:68,337,316 | C/T | — | uncertain significance |
| rs566852299 | 11:68,337,327 | G/A | — | uncertain significance |
| rs756785027 | 11:68,338,508 | C/A | — | uncertain significance |
| rs1213033425 | 11:68,341,578 | G/T | — | uncertain significance |
| rs374733086 | 11:68,341,588 | G/A | — | uncertain significance |
| rs753688721 | 11:68,341,638 | G/A | — | uncertain significance |
| rs770018481 | 11:68,341,669 | C/T | — | uncertain significance |
| rs370247087 | 11:68,343,432 | C/G | — | uncertain significance |
| rs771453632 | 11:68,343,434 | G/A | — | uncertain significance |
| rs897821545 | 11:68,343,510 | T/C | — | uncertain significance |
| rs1452608346 | 11:68,350,530 | A/G | — | uncertain significance |
| rs777342171 | 11:68,350,566 | C/T | — | uncertain significance |
| rs1229077593 | 11:68,355,426 | C/T | — | uncertain significance |
| rs150095519 | 11:68,358,142 | G/A | — | uncertain significance |
| rs1273697911 | 11:68,358,169 | A/G | — | uncertain significance |
| rs2099595623 | 11:68,359,074 | A/C | — | uncertain significance |
| rs772404927 | 11:68,359,171 | C/T | — | uncertain significance |
| rs763937581 | 11:68,363,567 | C/T | — | uncertain significance |
| rs3758644 | 11:68,366,088 | C/T | intron variant | — |
| rs765315647 | 11:68,367,838 | C/A | — | uncertain significance |
| rs1279841262 | 11:68,369,345 | T/C | — | uncertain significance |
| rs7927592 | 11:68,369,960 | G/A | intron variant | — |
| rs917321447 | 11:68,370,857 | G/A | — | uncertain significance |
| rs937273483 | 11:68,377,463 | A/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.