PRDM14
PR/SET domain 14
Summary
This gene encodes a member of the PRDI-BF1 and RIZ homology domain containing (PRDM) family of transcriptional regulators. The encoded protein may possess histone methyltransferase activity and plays a critical role in cell pluripotency by suppressing the expression of differentiation marker genes. Expression of this gene may play a role in breast cancer. [provided by RefSeq, Dec 2011]
Known Variants23 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs750955424 | 8:70,964,367 | A/T | — | uncertain significance |
| rs1805397631 | 8:70,964,472 | C/T | — | uncertain significance |
| rs7016464 | 8:70,970,809 | C/T | — | — |
| rs558624966 | 8:70,970,931 | G/A | — | uncertain significance |
| rs7010162 | 8:70,976,505 | C/G | — | — |
| rs141769540 | 8:70,978,499 | G/A | — | uncertain significance |
| rs2487801512 | 8:70,980,572 | A/G | — | uncertain significance |
| rs553575533 | 8:70,980,596 | C/T | — | uncertain significance |
| rs2487801538 | 8:70,980,602 | C/A | — | uncertain significance |
| rs1036596459 | 8:70,980,604 | G/A | — | uncertain significance |
| rs2487802595 | 8:70,981,483 | C/T | — | uncertain significance |
| rs774593313 | 8:70,981,568 | C/G | — | uncertain significance |
| rs140792769 | 8:70,981,681 | C/T | — | uncertain significance |
| rs757399327 | 8:70,981,743 | C/G | — | uncertain significance |
| rs762978275 | 8:70,981,805 | C/A | — | uncertain significance |
| rs1436592648 | 8:70,981,819 | G/A | — | uncertain significance |
| rs2487803458 | 8:70,981,882 | G/A | — | uncertain significance |
| rs747517389 | 8:70,981,888 | G/A | — | uncertain significance |
| rs2487803475 | 8:70,981,894 | G/A | — | uncertain significance |
| rs2487803500 | 8:70,981,906 | G/A | — | uncertain significance |
| rs992179850 | 8:70,981,915 | A/C | — | uncertain significance |
| rs138348268 | 8:70,981,935 | C/T | — | uncertain significance |
| rs149635847 | 8:70,981,938 | A/C | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.