PRDM15
PR/SET domain 15
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and promoter-specific chromatin binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II; regulation of signal transduction; and regulation of stem cell division. Located in nuclear body. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants110 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs1054761 | 21:43,218,520 | G/A | downstream gene variant | — |
| rs2517381857 | 21:43,221,405 | A/T | — | uncertain significance |
| rs147616045 | 21:43,221,434 | G/A | — | uncertain significance |
| rs771684064 | 21:43,221,513 | C/T | — | uncertain significance |
| rs200853879 | 21:43,221,520 | C/T | — | likely benign |
| rs116436673 | 21:43,221,580 | C/T | — | likely benign |
| rs138426773 | 21:43,221,611 | G/C | — | uncertain significance |
| rs373004514 | 21:43,221,626 | G/A | — | uncertain significance |
| rs2517387066 | 21:43,221,629 | T/A | — | uncertain significance |
| rs145309149 | 21:43,221,794 | G/A | — | uncertain significance |
| rs74706304 | 21:43,221,816 | T/A | — | uncertain significance |
| rs996045746 | 21:43,221,842 | G/A | — | uncertain significance |
| rs2517392143 | 21:43,221,858 | T/G | — | uncertain significance |
| rs535368225 | 21:43,223,036 | C/T | — | uncertain significance |
| rs372762092 | 21:43,223,048 | C/T | — | uncertain significance |
| rs62216224 | 21:43,223,583 | C/A | — | — |
| rs77634221 | 21:43,223,696 | G/A | intron variant | — |
| rs759735465 | 21:43,224,720 | C/T | — | uncertain significance |
| rs7279297 | 21:43,227,915 | A/G | intron variant | — |
| rs763999852 | 21:43,230,656 | C/T | — | uncertain significance |
| rs755894771 | 21:43,230,662 | C/T | — | uncertain significance |
| rs749197090 | 21:43,230,666 | G/A | — | likely benign |
| rs146699277 | 21:43,230,669 | C/T | — | likely benign |
| rs2061840290 | 21:43,231,165 | C/T | — | likely pathogenic |
| rs775233819 | 21:43,236,063 | G/A | — | uncertain significance |
| rs1325006511 | 21:43,236,069 | C/T | — | uncertain significance |
| rs146647341 | 21:43,236,119 | C/G | — | uncertain significance |
| rs1568908419 | 21:43,236,139 | T/C | — | uncertain significance |
| rs4075967 | 21:43,236,176 | G/A | synonymous variant | — |
| rs758137031 | 21:43,239,967 | C/T | — | uncertain significance |
| rs1297604707 | 21:43,239,985 | C/T | — | uncertain significance |
| rs759441794 | 21:43,241,454 | G/A | — | uncertain significance |
| rs569854976 | 21:43,242,323 | T/G | — | uncertain significance |
| rs558527785 | 21:43,242,351 | C/T | — | uncertain significance |
| rs748263943 | 21:43,242,354 | T/C | — | uncertain significance |
| rs1434935886 | 21:43,242,387 | C/G | — | uncertain significance |
| rs750430962 | 21:43,243,726 | C/T | — | uncertain significance |
| rs748741564 | 21:43,246,356 | C/T | — | uncertain significance |
| rs768225892 | 21:43,246,357 | G/A | — | uncertain significance |
| rs143116534 | 21:43,246,366 | T/C | — | uncertain significance |
| rs1324051429 | 21:43,246,401 | C/T | — | uncertain significance |
| rs182759790 | 21:43,248,552 | T/C | — | uncertain significance |
| rs142468830 | 21:43,248,564 | G/A | — | uncertain significance |
| rs762102628 | 21:43,248,609 | C/T | — | uncertain significance |
| rs376443140 | 21:43,255,573 | C/T | — | uncertain significance |
| rs151294336 | 21:43,255,606 | C/T | — | uncertain significance |
| rs901074349 | 21:43,256,272 | G/A | — | uncertain significance |
| rs762573727 | 21:43,256,287 | C/T | — | uncertain significance |
| rs781632486 | 21:43,256,664 | C/G | — | uncertain significance |
| rs1446642027 | 21:43,256,669 | T/G | — | uncertain significance |
| rs907095356 | 21:43,256,697 | G/A | — | uncertain significance |
| rs2517824040 | 21:43,256,727 | G/A | — | uncertain significance |
| rs764627146 | 21:43,256,729 | G/A | — | uncertain significance |
| rs142611293 | 21:43,256,734 | G/A | — | likely benign |
| rs576343480 | 21:43,258,135 | A/C | — | uncertain significance |
| rs750122550 | 21:43,258,139 | G/A | — | uncertain significance |
| rs766337936 | 21:43,258,149 | C/T | — | uncertain significance |
| rs753793845 | 21:43,258,150 | G/A | — | likely benign |
| rs200127182 | 21:43,259,753 | C/T | — | likely benign |
| rs749820707 | 21:43,259,758 | A/G | — | uncertain significance |
| rs751662230 | 21:43,259,803 | C/T | — | uncertain significance |
| rs201285981 | 21:43,259,911 | T/C | — | uncertain significance |
| rs1202184408 | 21:43,259,912 | G/C | — | uncertain significance |
| rs78882046 | 21:43,267,201 | T/C | — | uncertain significance |
| rs1363086298 | 21:43,267,251 | C/A | — | uncertain significance |
| rs1163591326 | 21:43,267,270 | A/C | — | uncertain significance |
| rs2063292924 | 21:43,267,298 | C/T | — | uncertain significance |
| rs7281772 | 21:43,269,412 | C/G | — | — |
| rs112277078 | 21:43,271,847 | C/T | intron variant | — |
| rs140468382 | 21:43,274,693 | C/T | — | likely benign |
| rs138083588 | 21:43,274,798 | C/T | — | uncertain significance |
| rs141612018 | 21:43,274,895 | G/A | — | likely benign |
| rs144512432 | 21:43,274,903 | C/T | — | uncertain significance |
| rs200141086 | 21:43,274,905 | G/C | — | uncertain significance |
| rs915832 | 21:43,275,495 | A/G | intron variant | — |
| rs200403538 | 21:43,277,296 | A/G | — | uncertain significance |
| rs780443036 | 21:43,277,358 | T/C | — | uncertain significance |
| rs376110395 | 21:43,279,152 | A/T | — | uncertain significance |
| rs2063729782 | 21:43,279,177 | T/G | — | likely benign |
| rs1303634328 | 21:43,279,199 | C/A | — | uncertain significance |
| rs1220247310 | 21:43,279,216 | G/A | — | uncertain significance |
| rs142772562 | 21:43,280,455 | G/A | — | likely benign |
| rs929796453 | 21:43,280,469 | C/T | — | uncertain significance |
| rs142753758 | 21:43,281,673 | G/A | — | uncertain significance |
| rs62621406 | 21:43,281,767 | A/C | — | likely benign |
| rs144911690 | 21:43,281,777 | C/T | — | likely benign |
| rs576406672 | 21:43,281,788 | C/A | — | uncertain significance |
| rs766922466 | 21:43,282,035 | T/G | — | uncertain significance |
| rs371480422 | 21:43,282,086 | T/A | — | uncertain significance |
| rs201042650 | 21:43,282,090 | C/T | — | uncertain significance |
| rs748278229 | 21:43,282,096 | C/T | — | uncertain significance |
| rs202208616 | 21:43,282,108 | C/T | — | uncertain significance |
| rs2839398 | 21:43,286,352 | C/A | — | — |
| rs1176160785 | 21:43,287,429 | C/T | — | uncertain significance |
| rs769179572 | 21:43,287,484 | G/T | — | uncertain significance |
| rs374855659 | 21:43,291,624 | G/A | — | uncertain significance |
| rs750609158 | 21:43,291,642 | C/T | — | uncertain significance |
| rs547995379 | 21:43,291,708 | C/A | — | uncertain significance |
| rs370060965 | 21:43,298,847 | C/G | — | uncertain significance |
| rs1360054459 | 21:43,298,867 | G/C | — | uncertain significance |
Showing 100 of 110 variants. Use the SNP search for the full list.
Gene information from NCBI Gene. Variant classifications from ClinVar.