PTGR3

prostaglandin reductase 3

Summary

Predicted to enable 15-oxoprostaglandin 13-oxidase [NAD(P)+] activity. Predicted to be involved in negative regulation of fat cell differentiation. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]

Known Variants27 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs634687	18:72,906,960	T/G	downstream gene variant	—
rs757955275	18:72,913,384	T/G	—	uncertain significance
rs372819128	18:72,913,435	T/A	—	uncertain significance
rs147233998	18:72,913,453	C/A	—	uncertain significance
rs763668764	18:72,913,466	C/T	—	uncertain significance
rs140713450	18:72,913,506	G/C	—	uncertain significance
rs2511866527	18:72,913,541	T/A	—	uncertain significance
rs762391408	18:72,913,544	C/T	—	likely benign
rs141337829	18:72,913,642	G/A	—	uncertain significance
rs534224169	18:72,913,660	G/A	—	uncertain significance
rs1220289397	18:72,913,669	G/A	—	uncertain significance
rs146651397	18:72,913,771	T/C	—	uncertain significance
rs1002604887	18:72,913,841	T/C	—	uncertain significance
rs143468645	18:72,913,885	T/G	—	uncertain significance
rs766437241	18:72,913,954	C/T	—	uncertain significance
rs1034445520	18:72,914,032	G/A	—	uncertain significance
rs1430270722	18:72,914,159	T/C	—	uncertain significance
rs149346224	18:72,914,203	A/G	—	uncertain significance
rs768718857	18:72,914,231	G/C	—	uncertain significance
rs1215256225	18:72,914,279	C/T	—	uncertain significance
rs2639990	18:72,915,551	T/C	intron variant	—
rs899535485	18:72,920,812	G/A	—	uncertain significance
rs2511874588	18:72,920,860	T/G	—	likely benign
rs201759106	18:72,920,865	G/T	—	uncertain significance
rs763670392	18:72,920,896	G/A	—	uncertain significance
rs752787245	18:72,920,922	T/A	—	uncertain significance
rs777008296	18:72,920,980	T/C	—	uncertain significance

Gene information from NCBI Gene. Variant classifications from ClinVar.