PURG
purine rich element binding protein G
Summary
The exact function of this gene is not known, however, its encoded product is highly similar to purine-rich element binding protein A. The latter is a DNA-binding protein which binds preferentially to the single strand of the purine-rich element termed PUR, and has been implicated in the control of both DNA replication and transcription. This gene lies in close proximity to the Werner syndrome gene, but on the opposite strand, on chromosome 8p11. [provided by RefSeq, Apr 2016]
Known Variants18 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs12234936 | 8:30,857,668 | T/C | intron variant | — |
| rs779485500 | 8:30,889,287 | C/A | — | uncertain significance |
| rs2487158563 | 8:30,889,289 | T/C | — | likely benign |
| rs541236532 | 8:30,889,373 | C/T | — | uncertain significance |
| rs2487159501 | 8:30,889,472 | A/T | — | uncertain significance |
| rs765564331 | 8:30,889,481 | C/T | — | uncertain significance |
| rs369086930 | 8:30,889,526 | G/A | — | uncertain significance |
| rs745662043 | 8:30,889,541 | C/A | — | uncertain significance |
| rs771968873 | 8:30,889,547 | C/T | — | uncertain significance |
| rs1311927652 | 8:30,889,688 | C/T | — | uncertain significance |
| rs374671334 | 8:30,889,695 | T/C | — | uncertain significance |
| rs2487161135 | 8:30,889,778 | T/C | — | likely benign |
| rs753826470 | 8:30,889,961 | G/A | — | uncertain significance |
| rs2487163531 | 8:30,890,190 | A/G | — | uncertain significance |
| rs1479221599 | 8:30,890,231 | G/C | — | uncertain significance |
| rs566964162 | 8:30,890,262 | G/C | — | uncertain significance |
| rs768857757 | 8:30,890,277 | C/T | — | uncertain significance |
| rs1297554624 | 8:30,890,282 | C/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.