PWWP2A
PWWP domain containing 2A
Summary
Enables NuRD complex binding activity; chromatin binding activity; and methylated histone binding activity. Involved in chromatin remodeling. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Known Variants30 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs763371154 | 5:159,507,748 | T/G | — | uncertain significance |
| rs4582322 | 5:159,509,400 | G/T | intron variant | — |
| rs185682695 | 5:159,519,425 | G/A | — | likely benign |
| rs1004667235 | 5:159,519,468 | T/C | — | uncertain significance |
| rs1180280165 | 5:159,519,667 | A/G | — | uncertain significance |
| rs2480301836 | 5:159,519,736 | T/G | — | uncertain significance |
| rs781471964 | 5:159,519,748 | C/T | — | likely benign |
| rs373887220 | 5:159,519,777 | T/C | — | uncertain significance |
| rs1271271347 | 5:159,519,779 | C/G | — | uncertain significance |
| rs1183914341 | 5:159,519,816 | G/C | — | uncertain significance |
| rs931943898 | 5:159,519,933 | G/T | — | uncertain significance |
| rs377359788 | 5:159,519,953 | C/T | — | uncertain significance |
| rs58423476 | 5:159,519,956 | A/G | — | benign |
| rs374725441 | 5:159,520,013 | A/C | — | likely benign |
| rs569407963 | 5:159,520,084 | T/C | — | uncertain significance |
| rs1183879178 | 5:159,520,174 | C/T | — | uncertain significance |
| rs555008097 | 5:159,520,182 | G/A | — | uncertain significance |
| rs371543221 | 5:159,520,305 | T/C | — | uncertain significance |
| rs765314531 | 5:159,520,396 | T/C | — | uncertain significance |
| rs2480313134 | 5:159,520,534 | T/C | — | uncertain significance |
| rs1755349735 | 5:159,520,954 | C/T | — | uncertain significance |
| rs2480320009 | 5:159,521,059 | C/T | — | uncertain significance |
| rs199993544 | 5:159,545,891 | T/C | — | uncertain significance |
| rs778681728 | 5:159,545,942 | T/C | — | likely benign |
| rs1053737386 | 5:159,545,995 | G/A | — | uncertain significance |
| rs368799133 | 5:159,546,183 | T/C | — | benign |
| rs769295767 | 5:159,546,187 | G/A | — | uncertain significance |
| rs1048815769 | 5:159,546,217 | G/T | — | uncertain significance |
| rs1758490099 | 5:159,546,373 | G/A | — | uncertain significance |
| rs1466738209 | 5:159,546,380 | C/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.