QSOX1
quiescin sulfhydryl oxidase 1
Summary
This gene encodes a protein that contains domains of thioredoxin and ERV1, members of two long-standing gene families. The gene expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Known Variants64 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs376772000 | 1:180,123,891 | T/G | — | — |
| rs1272286332 | 1:180,124,050 | G/A | — | uncertain significance |
| rs1230185669 | 1:180,124,073 | C/T | — | uncertain significance |
| rs763224419 | 1:180,124,077 | C/T | — | uncertain significance |
| rs767868738 | 1:180,124,110 | C/T | — | uncertain significance |
| rs1270799822 | 1:180,124,133 | C/T | — | uncertain significance |
| rs550709452 | 1:180,124,136 | C/T | — | uncertain significance |
| rs1028409575 | 1:180,124,163 | C/A | — | uncertain significance |
| rs1159327330 | 1:180,124,188 | C/A | — | uncertain significance |
| rs77647137 | 1:180,124,288 | G/T | synonymous variant | — |
| rs1438908648 | 1:180,124,293 | C/A | — | uncertain significance |
| rs55946907 | 1:180,130,723 | C/T | intron variant | — |
| rs1057441838 | 1:180,135,644 | A/G | — | uncertain significance |
| rs201825048 | 1:180,135,652 | G/A | — | uncertain significance |
| rs149269903 | 1:180,135,672 | G/C | — | uncertain significance |
| rs772042431 | 1:180,135,683 | C/T | — | uncertain significance |
| rs3894211 | 1:180,135,701 | A/G | — | benign |
| rs150472198 | 1:180,137,839 | A/G | regulatory region variant | — |
| rs538917832 | 1:180,144,470 | T/C | — | likely benign |
| rs377697828 | 1:180,144,480 | G/A | — | uncertain significance |
| rs200899348 | 1:180,145,132 | C/T | — | uncertain significance |
| rs775600138 | 1:180,145,152 | C/T | — | uncertain significance |
| rs374697697 | 1:180,147,922 | C/T | — | likely benign |
| rs768327518 | 1:180,147,961 | A/G | — | uncertain significance |
| rs774680958 | 1:180,147,994 | A/C | — | uncertain significance |
| rs149484554 | 1:180,151,349 | G/A | — | uncertain significance |
| rs773645175 | 1:180,151,373 | A/G | — | uncertain significance |
| rs1465095299 | 1:180,153,068 | C/T | — | uncertain significance |
| rs377358722 | 1:180,153,070 | T/C | — | uncertain significance |
| rs760547195 | 1:180,153,074 | A/G | — | uncertain significance |
| rs140969999 | 1:180,153,134 | C/G | — | uncertain significance |
| rs200808149 | 1:180,155,259 | C/T | — | uncertain significance |
| rs144365485 | 1:180,155,323 | C/A | — | benign |
| rs147174133 | 1:180,158,740 | G/T | — | uncertain significance |
| rs61736297 | 1:180,159,621 | G/A | — | benign |
| rs376323339 | 1:180,159,648 | G/A | — | likely benign |
| rs148289660 | 1:180,163,385 | C/T | — | likely benign |
| rs778400897 | 1:180,163,436 | G/A | — | uncertain significance |
| rs546683425 | 1:180,163,456 | G/A | — | uncertain significance |
| rs143337247 | 1:180,163,458 | G/A | — | uncertain significance |
| rs1572055922 | 1:180,163,459 | T/A | — | uncertain significance |
| rs370455042 | 1:180,163,476 | G/T | — | uncertain significance |
| rs111738446 | 1:180,165,387 | C/T | — | benign |
| rs774684977 | 1:180,165,445 | G/T | — | uncertain significance |
| rs777266980 | 1:180,165,489 | G/A | — | uncertain significance |
| rs1663488878 | 1:180,165,547 | T/A | — | uncertain significance |
| rs1333967488 | 1:180,165,561 | C/G | — | uncertain significance |
| rs2528090383 | 1:180,165,604 | C/T | — | uncertain significance |
| rs371276500 | 1:180,165,648 | C/T | — | uncertain significance |
| rs1421233131 | 1:180,165,657 | A/G | — | uncertain significance |
| rs368869048 | 1:180,165,666 | C/T | — | uncertain significance |
| rs2528090605 | 1:180,165,678 | G/A | — | uncertain significance |
| rs377701409 | 1:180,165,709 | C/G | — | uncertain significance |
| rs145708234 | 1:180,165,718 | C/T | — | benign |
| rs16855466 | 1:180,165,742 | G/C | — | benign |
| rs188075416 | 1:180,165,772 | C/T | — | uncertain significance |
| rs199822437 | 1:180,165,835 | C/T | — | uncertain significance |
| rs1157050302 | 1:180,165,871 | G/A | — | uncertain significance |
| rs1572057632 | 1:180,165,873 | G/T | — | uncertain significance |
| rs3738114 | 1:180,165,947 | C/A | — | benign |
| rs539208834 | 1:180,166,136 | G/C | — | uncertain significance |
| rs1191026986 | 1:180,166,140 | C/G | — | uncertain significance |
| rs372495097 | 1:180,166,150 | A/G | — | uncertain significance |
| rs4652482 | 1:180,166,631 | G/A | 3 prime UTR variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.