RANGAP1
Ran GTPase activating protein 1
Summary
This gene encodes a protein that associates with the nuclear pore complex and participates in the regulation of nuclear transport. The encoded protein interacts with Ras-related nuclear protein 1 (RAN) and regulates guanosine triphosphate (GTP)-binding and exchange. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Known Variants42 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs201423590 | 22:41,642,642 | G/A | — | uncertain significance |
| rs139498 | 22:41,644,234 | G/C | intron variant | — |
| rs9611527 | 22:41,644,428 | G/C | — | — |
| rs200464078 | 22:41,645,341 | C/T | — | likely benign |
| rs1305290282 | 22:41,645,394 | A/G | — | uncertain significance |
| rs764740821 | 22:41,645,406 | G/A | — | uncertain significance |
| rs367631916 | 22:41,645,407 | C/T | — | uncertain significance |
| rs939862654 | 22:41,645,433 | A/G | — | uncertain significance |
| rs770249841 | 22:41,645,753 | C/T | — | uncertain significance |
| rs200191945 | 22:41,647,049 | T/C | — | uncertain significance |
| rs140617608 | 22:41,650,346 | G/A | — | uncertain significance |
| rs145681292 | 22:41,650,352 | G/A | — | uncertain significance |
| rs2229755 | 22:41,650,371 | G/C | — | benign |
| rs779021375 | 22:41,650,392 | C/T | — | uncertain significance |
| rs369523575 | 22:41,650,410 | C/T | — | uncertain significance |
| rs1229718293 | 22:41,650,464 | C/T | — | uncertain significance |
| rs1601604945 | 22:41,650,480 | C/G | — | likely benign |
| rs777969995 | 22:41,652,095 | C/T | — | uncertain significance |
| rs202097810 | 22:41,652,227 | T/C | — | uncertain significance |
| rs2033823701 | 22:41,652,228 | C/T | — | uncertain significance |
| rs2066780 | 22:41,652,250 | T/C | — | benign |
| rs1411472389 | 22:41,652,721 | C/G | — | uncertain significance |
| rs543983054 | 22:41,652,731 | C/G | — | uncertain significance |
| rs148624391 | 22:41,652,753 | T/C | — | uncertain significance |
| rs772732178 | 22:41,654,034 | G/C | — | uncertain significance |
| rs1354705014 | 22:41,654,051 | G/C | — | uncertain significance |
| rs779095439 | 22:41,654,058 | G/A | — | uncertain significance |
| rs773051597 | 22:41,654,080 | G/T | — | uncertain significance |
| rs35445172 | 22:41,660,301 | G/A | — | — |
| rs2229752 | 22:41,660,751 | C/T | — | uncertain significance |
| rs2517990456 | 22:41,660,781 | C/T | — | uncertain significance |
| rs143626610 | 22:41,660,826 | T/C | — | uncertain significance |
| rs2235852 | 22:41,661,154 | G/C | — | — |
| rs1376012009 | 22:41,664,147 | C/T | — | uncertain significance |
| rs1234938730 | 22:41,664,159 | C/T | — | uncertain significance |
| rs758368926 | 22:41,670,611 | T/C | — | uncertain significance |
| rs2518025813 | 22:41,670,651 | C/T | — | uncertain significance |
| rs539682211 | 22:41,670,657 | C/T | — | uncertain significance |
| rs9611540 | 22:41,674,203 | C/A | — | — |
| rs201728257 | 22:41,676,991 | C/T | — | uncertain significance |
| rs8139705 | 22:41,680,898 | C/T | — | benign |
| rs4822020 | 22:41,700,203 | C/T | intron variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.