RASSF3
Ras association domain family member 3
Summary
The RAS oncogene (MIM 190020) is mutated in nearly one-third of all human cancers. Members of the RAS superfamily are plasma membrane GTP-binding proteins that modulate intracellular signal transduction pathways. A subfamily of RAS effectors, including RASSF3, share a RAS association (RA) domain.[supplied by OMIM, Jul 2003]
Known Variants26 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs867400 | 12:64,976,850 | T/A | — | — |
| rs76152526 | 12:64,978,282 | A/C | — | — |
| rs7969980 | 12:64,979,998 | A/G | intergenic variant | — |
| rs6581580 | 12:65,002,969 | T/C | — | — |
| rs1870316125 | 12:65,004,442 | G/C | — | uncertain significance |
| rs12818251 | 12:65,007,107 | G/A | upstream gene variant | — |
| rs113373353 | 12:65,007,682 | C/T | regulatory region variant | — |
| rs7313765 | 12:65,011,980 | G/A | upstream gene variant | — |
| rs12311754 | 12:65,013,789 | G/C | regulatory region variant | — |
| rs1147098 | 12:65,015,244 | G/A | regulatory region variant | — |
| rs77545561 | 12:65,016,166 | T/C | upstream gene variant | — |
| rs17120527 | 12:65,016,300 | A/G | coding sequence variant | — |
| rs78689302 | 12:65,033,149 | T/G | — | — |
| rs11175502 | 12:65,045,698 | C/T | downstream gene variant | — |
| rs77906229 | 12:65,066,544 | C/T | regulatory region variant | — |
| rs1014314878 | 12:65,078,621 | G/C | — | uncertain significance |
| rs762074862 | 12:65,078,664 | A/G | — | uncertain significance |
| rs1309278039 | 12:65,082,053 | C/G | — | uncertain significance |
| rs61743229 | 12:65,082,068 | A/G | — | uncertain significance |
| rs777780609 | 12:65,082,129 | C/G | — | uncertain significance |
| rs774662298 | 12:65,082,152 | G/A | — | uncertain significance |
| rs753818639 | 12:65,085,343 | A/G | — | uncertain significance |
| rs2539478589 | 12:65,085,349 | A/C | — | uncertain significance |
| rs141300071 | 12:65,088,591 | G/C | — | uncertain significance |
| rs374075980 | 12:65,088,637 | C/G | — | uncertain significance |
| rs766150447 | 12:65,088,639 | G/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.