RBM14-RBM4
RBM14-RBM4 readthrough
Summary
This locus represents naturally occurring read-through transcription between the neighboring RBM14 (RNA binding motif protein 14) and RBM4 (RNA binding motif protein 4) genes. Alternative splicing results in multiple transcript variants, one of which encodes a fusion protein that shares sequence identity with each individual gene product. This fusion protein contains RRM and zinc finger domains, and it functions to stimulate transcription in a hormone and receptor-dependent manner. [provided by RefSeq, Nov 2010]
Known Variants4 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs141638488 | 11:66,403,798 | T/G | upstream gene variant | — |
| rs777170299 | 11:66,411,220 | G/A | — | uncertain significance |
| rs775910343 | 11:66,411,384 | C/T | — | likely benign |
| rs2495501907 | 11:66,411,407 | C/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.