RCOR1

REST corepressor 1

Summary

This gene encodes a protein that is well-conserved, downregulated at birth, and with a specific role in determining neural cell differentiation. The encoded protein binds to the C-terminal domain of REST (repressor element-1 silencing transcription factor). [provided by RefSeq, Aug 2011]

Known Variants58 total

rsidPosition (GRCh37)AllelesClassClinVar
rs14251264514:103,058,644G/Aregulatory region variant—
rs3525812014:103,058,769G/T——
rs115764107614:103,059,231C/A—uncertain significance
rs189315811214:103,059,258C/T—uncertain significance
rs75358212714:103,059,291C/T—uncertain significance
rs119633532214:103,059,292C/T—likely benign
rs100449626914:103,059,299T/G—uncertain significance
rs56939965514:103,059,316C/T—likely benign
rs189316177714:103,059,330C/T—uncertain significance
rs117108222614:103,059,356G/A—uncertain significance
rs189316337114:103,059,361C/T—likely benign
rs250463062514:103,059,404G/T—uncertain significance
rs53851089514:103,059,415C/T—likely benign
rs77273262514:103,059,420A/G—uncertain significance
rs105436699014:103,059,427C/T—likely benign
rs250463095714:103,059,506T/A—uncertain significance
rs5850772414:103,060,637G/Aintron variant—
rs214642914:103,071,816A/C——
rs240306814:103,073,533G/C——
rs490623414:103,076,928G/Cintron variant—
rs2851997114:103,089,808C/Tintron variant—
rs36976138914:103,089,820A/G——
rs1288479314:103,095,785C/A——
rs1162775614:103,096,606C/Tregulatory region variant—
rs54027138414:103,099,891C/T——
rs14609113314:103,106,224C/Gintron variant—
rs18785309014:103,110,511C/Tintron variant—
rs55833662414:103,128,151T/G——
rs7270276114:103,147,309C/Tintron variant—
rs250374033214:103,148,270G/T—uncertain significance
rs14928207614:103,148,302G/C—likely benign
rs11718693414:103,162,893G/Tdownstream gene variant—
rs75440487914:103,167,612C/T—likely pathogenic
rs75218755714:103,167,631C/T—likely benign
rs7664152114:103,167,676A/G—benign
rs57815277314:103,171,468C/A——
rs53298305114:103,173,627C/T——
rs14941882914:103,173,756C/A—benign
rs75351372414:103,174,857C/T—uncertain significance
rs14603432214:103,174,858G/A—likely benign
rs189590069314:103,174,883C/T—uncertain significance
rs78124607914:103,174,892C/T—uncertain significance
rs77045478114:103,177,287A/G—likely benign
rs76638042914:103,180,754A/T—likely benign
rs75388491314:103,180,765C/T—likely benign
rs75887612314:103,180,864A/G—likely benign
rs250379709214:103,180,895A/G—uncertain significance
rs250379729714:103,180,966C/A—likely benign
rs37719066314:103,180,973T/G—likely benign
rs20168880014:103,187,355T/C—benign
rs74840523414:103,187,731C/A—likely benign
rs77800821314:103,188,511C/T—likely benign
rs36817076314:103,188,515C/T—likely benign
rs75943173714:103,188,680C/G—uncertain significance
rs14670664814:103,188,683A/G—benign
rs6173937414:103,188,738T/C—benign
rs120803046214:103,188,748G/A—uncertain significance
rs77157658614:103,192,790T/C—likely benign

Gene information from NCBI Gene. Variant classifications from ClinVar.