RHEX
regulator of hemoglobinization and erythroid cell expansion
Summary
Enables erythropoietin receptor binding activity. Involved in erythropoietin-mediated signaling pathway and positive regulation of erythrocyte differentiation. Located in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants14 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs28602496 | 1:206,239,403 | C/T | — | benign |
| rs28639473 | 1:206,239,415 | C/T | — | benign |
| rs116565072 | 1:206,239,549 | C/T | — | benign |
| rs28391411 | 1:206,239,574 | T/C | — | benign |
| rs75501563 | 1:206,240,149 | C/T | — | benign |
| rs147914249 | 1:206,240,188 | G/A | — | likely benign |
| rs140623711 | 1:206,241,561 | G/A | — | likely benign |
| rs115353955 | 1:206,241,650 | C/T | — | benign |
| rs111456444 | 1:206,243,143 | C/A | — | benign |
| rs2526777542 | 1:206,243,230 | C/G | — | uncertain significance |
| rs115231339 | 1:206,246,161 | G/A | intron variant | — |
| rs182243558 | 1:206,264,784 | T/A | upstream gene variant | — |
| rs77172677 | 1:206,268,507 | C/G | — | — |
| rs142133048 | 1:206,270,067 | G/A | intron variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.