RHPN2
rhophilin Rho GTPase binding protein 2
Summary
This gene encodes a member of the rhophilin family of Ras-homologous (Rho)-GTPase binding proteins. The encoded protein binds both GTP- and GDP-bound RhoA and GTP-bound RhoB and may be involved in the organization of the actin cytoskeleton. [provided by RefSeq, Apr 2009]
Known Variants62 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs1308048021 | 19:33,470,921 | G/A | — | uncertain significance |
| rs147541207 | 19:33,470,924 | T/C | — | uncertain significance |
| rs2513801042 | 19:33,470,954 | T/C | — | uncertain significance |
| rs759812870 | 19:33,471,066 | T/G | — | uncertain significance |
| rs147967421 | 19:33,471,138 | C/T | — | uncertain significance |
| rs746894075 | 19:33,481,470 | C/A | — | uncertain significance |
| rs183236318 | 19:33,481,563 | G/A | — | uncertain significance |
| rs769469341 | 19:33,482,800 | C/T | — | uncertain significance |
| rs79314177 | 19:33,482,821 | G/A | — | benign |
| rs750379907 | 19:33,482,844 | C/T | — | uncertain significance |
| rs138451485 | 19:33,484,901 | C/T | — | likely benign |
| rs2513809269 | 19:33,484,920 | A/G | — | uncertain significance |
| rs138153671 | 19:33,486,989 | C/T | — | likely benign |
| rs75351369 | 19:33,486,992 | A/C | — | benign |
| rs2513810394 | 19:33,487,003 | G/A | — | uncertain significance |
| rs1200277520 | 19:33,487,045 | A/G | — | uncertain significance |
| rs141232995 | 19:33,487,052 | G/A | — | uncertain significance |
| rs370605415 | 19:33,487,063 | C/A | — | uncertain significance |
| rs139766778 | 19:33,487,072 | G/A | — | uncertain significance |
| rs774798877 | 19:33,487,078 | C/T | — | uncertain significance |
| rs11084689 | 19:33,487,182 | A/G | regulatory region variant | — |
| rs201844789 | 19:33,490,510 | G/C | — | uncertain significance |
| rs1568312930 | 19:33,493,203 | T/C | — | uncertain significance |
| rs767959366 | 19:33,493,219 | C/T | — | uncertain significance |
| rs139839345 | 19:33,493,221 | C/T | — | uncertain significance |
| rs145677315 | 19:33,493,224 | G/A | — | uncertain significance |
| rs28407794 | 19:33,493,234 | C/G | — | benign |
| rs2513814064 | 19:33,493,246 | G/A | — | uncertain significance |
| rs2513814107 | 19:33,493,285 | G/A | — | uncertain significance |
| rs201787348 | 19:33,493,711 | A/G | — | likely benign |
| rs757081366 | 19:33,493,765 | C/T | — | likely benign |
| rs151179227 | 19:33,493,778 | G/A | — | uncertain significance |
| rs772227567 | 19:33,493,790 | C/T | — | uncertain significance |
| rs1342283750 | 19:33,493,829 | C/T | — | uncertain significance |
| rs144820749 | 19:33,493,835 | C/T | — | benign |
| rs959667835 | 19:33,493,856 | T/A | — | uncertain significance |
| rs577697788 | 19:33,499,028 | T/A | — | conflicting classifications of pathogenicity |
| rs2513821004 | 19:33,502,613 | T/C | — | uncertain significance |
| rs373249916 | 19:33,502,699 | G/A | — | uncertain significance |
| rs779804803 | 19:33,502,713 | C/T | — | likely benign |
| rs1282773373 | 19:33,503,573 | C/A | — | uncertain significance |
| rs150703957 | 19:33,512,488 | C/T | — | uncertain significance |
| rs747224296 | 19:33,517,428 | C/T | — | uncertain significance |
| rs773144206 | 19:33,517,486 | C/T | — | uncertain significance |
| rs766442171 | 19:33,517,503 | C/T | — | uncertain significance |
| rs1470674201 | 19:33,517,525 | A/G | — | likely benign |
| rs8112217 | 19:33,518,718 | A/G | intron variant | — |
| rs73039426 | 19:33,520,961 | C/T | intron variant | — |
| rs73039428 | 19:33,521,150 | A/G | intron variant | — |
| rs73039434 | 19:33,524,919 | T/G | intron variant | — |
| rs10424333 | 19:33,527,596 | C/T | — | — |
| rs13343954 | 19:33,527,888 | T/C | intron variant | — |
| rs10411210 | 19:33,532,300 | C/T | regulatory region variant | — |
| rs371759693 | 19:33,535,185 | C/T | — | uncertain significance |
| rs747715669 | 19:33,535,201 | T/C | — | uncertain significance |
| rs182621702 | 19:33,537,201 | T/C | intron variant | — |
| rs7255601 | 19:33,549,775 | G/C | intron variant | — |
| rs11881367 | 19:33,551,428 | G/A | intron variant | — |
| rs926832944 | 19:33,555,704 | C/A | — | uncertain significance |
| rs1568330413 | 19:33,555,713 | C/T | — | uncertain significance |
| rs6510340 | 19:33,556,669 | A/G | — | — |
| rs8106453 | 19:33,557,412 | C/G | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.