RICTOR
RPTOR independent companion of MTOR complex 2
Summary
RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM, Mar 2008]
Known Variants58 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs769767383 | 5:38,945,092 | G/A | — | uncertain significance |
| rs144269248 | 5:38,945,615 | C/A | — | likely benign |
| rs2546635773 | 5:38,945,626 | T/A | — | uncertain significance |
| rs763579152 | 5:38,945,818 | A/G | — | uncertain significance |
| rs61748206 | 5:38,946,608 | T/C | — | uncertain significance |
| rs765850861 | 5:38,946,644 | A/C | — | uncertain significance |
| rs1748321916 | 5:38,947,451 | C/G | — | uncertain significance |
| rs774111455 | 5:38,949,526 | G/A | — | likely benign |
| rs141067436 | 5:38,949,868 | G/A | — | uncertain significance |
| rs138876503 | 5:38,950,028 | T/C | — | uncertain significance |
| rs2112848829 | 5:38,950,054 | C/T | — | uncertain significance |
| rs745589985 | 5:38,950,115 | G/C | — | uncertain significance |
| rs2112850501 | 5:38,950,150 | C/T | — | uncertain significance |
| rs747228448 | 5:38,950,202 | T/C | — | uncertain significance |
| rs544129708 | 5:38,950,401 | T/G | — | uncertain significance |
| rs61748209 | 5:38,950,489 | T/G | — | uncertain significance |
| rs770518141 | 5:38,950,637 | G/T | — | uncertain significance |
| rs1249602445 | 5:38,950,665 | C/G | — | uncertain significance |
| rs758778796 | 5:38,950,750 | T/C | — | uncertain significance |
| rs1748696722 | 5:38,950,822 | C/T | — | uncertain significance |
| rs945301712 | 5:38,952,418 | C/A | — | uncertain significance |
| rs61748210 | 5:38,952,527 | C/T | — | likely benign |
| rs200255149 | 5:38,953,162 | T/C | — | uncertain significance |
| rs143469898 | 5:38,953,625 | G/A | — | uncertain significance |
| rs111974076 | 5:38,954,955 | C/T | — | uncertain significance |
| rs140964083 | 5:38,955,743 | G/A | missense variant | — |
| rs1489359552 | 5:38,955,767 | G/A | — | uncertain significance |
| rs2043112 | 5:38,955,796 | G/A | missense variant | — |
| rs41271103 | 5:38,957,820 | A/T | — | benign |
| rs149642899 | 5:38,958,865 | A/G | — | benign |
| rs372934134 | 5:38,959,310 | G/C | — | uncertain significance |
| rs1749578068 | 5:38,959,346 | T/C | — | uncertain significance |
| rs768030162 | 5:38,959,360 | C/A | — | uncertain significance |
| rs202000202 | 5:38,959,883 | C/G | — | uncertain significance |
| rs751812891 | 5:38,959,924 | G/A | — | uncertain significance |
| rs369779198 | 5:38,962,634 | T/C | — | uncertain significance |
| rs374080869 | 5:38,963,082 | T/G | — | uncertain significance |
| rs755089256 | 5:38,964,910 | G/T | — | uncertain significance |
| rs2150027644 | 5:38,964,921 | G/A | — | uncertain significance |
| rs61734282 | 5:38,964,930 | A/G | — | uncertain significance |
| rs1750084043 | 5:38,964,955 | G/A | — | uncertain significance |
| rs1329438711 | 5:38,964,969 | T/C | — | likely pathogenic |
| rs2546693548 | 5:38,966,777 | C/T | — | uncertain significance |
| rs1750257443 | 5:38,966,813 | T/G | — | uncertain significance |
| rs770728330 | 5:38,967,280 | G/A | — | uncertain significance |
| rs200672374 | 5:38,967,451 | C/T | — | uncertain significance |
| rs376772272 | 5:38,967,464 | T/C | — | uncertain significance |
| rs761011163 | 5:38,967,507 | A/G | — | likely benign |
| rs777143677 | 5:38,968,098 | C/T | — | uncertain significance |
| rs148204602 | 5:38,977,033 | G/A | intron variant | — |
| rs551454961 | 5:38,984,150 | C/T | — | — |
| rs141745592 | 5:38,996,945 | T/C | — | likely benign |
| rs2546787395 | 5:39,002,676 | T/C | — | uncertain significance |
| rs751238829 | 5:39,002,683 | T/C | — | uncertain significance |
| rs1004942995 | 5:39,003,711 | A/G | — | uncertain significance |
| rs140903617 | 5:39,013,872 | G/A | intron variant | — |
| rs13160161 | 5:39,058,356 | G/A | intron variant | — |
| rs6869095 | 5:39,074,696 | C/T | regulatory region variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.