RND2
Rho family GTPase 2
Summary
This gene encodes a member of the Rho GTPase family, whose members play a key role in the regulation of actin cytoskeleton organization in response to extracellular growth factors. This particular family member has been implicated in the regulation of neuronal morphology and endosomal trafficking. The gene localizes to chromosome 17 and is the centromeric neighbor of the breast-ovarian cancer susceptibility gene BRCA1. [provided by RefSeq, Jul 2008]
Known Variants17 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs763612742 | 17:41,179,200 | G/T | — | uncertain significance |
| rs61756315 | 17:41,179,278 | G/A | — | uncertain significance |
| rs552149919 | 17:41,180,147 | C/T | — | uncertain significance |
| rs149254208 | 17:41,180,166 | T/C | — | uncertain significance |
| rs1248511975 | 17:41,180,196 | C/T | — | uncertain significance |
| rs535296435 | 17:41,180,503 | C/T | — | uncertain significance |
| rs2151974852 | 17:41,180,527 | G/A | — | uncertain significance |
| rs373981354 | 17:41,180,530 | G/A | — | uncertain significance |
| rs200578276 | 17:41,180,534 | T/A | — | uncertain significance |
| rs373748458 | 17:41,180,576 | A/G | — | uncertain significance |
| rs376927688 | 17:41,180,581 | C/T | — | uncertain significance |
| rs139946364 | 17:41,180,600 | G/A | — | uncertain significance |
| rs1390785704 | 17:41,180,605 | A/G | — | uncertain significance |
| rs143507179 | 17:41,180,612 | G/A | — | uncertain significance |
| rs368469044 | 17:41,180,632 | C/T | — | uncertain significance |
| rs779562018 | 17:41,180,633 | G/A | — | uncertain significance |
| rs9904909 | 17:41,181,898 | A/G | coding sequence variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.