RNF152
ring finger protein 152
Summary
Enables small GTPase binding activity and ubiquitin protein ligase activity. Involved in several processes, including cellular response to amino acid starvation; negative regulation of TORC1 signaling; and protein ubiquitination. Located in lysosomal membrane. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants19 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs776181105 | 18:59,483,165 | C/T | — | uncertain significance |
| rs371073949 | 18:59,483,219 | C/T | — | uncertain significance |
| rs375367742 | 18:59,483,225 | G/A | — | uncertain significance |
| rs753200247 | 18:59,483,228 | T/C | — | uncertain significance |
| rs569340864 | 18:59,483,272 | A/G | — | uncertain significance |
| rs374092992 | 18:59,483,300 | C/A | — | uncertain significance |
| rs368000636 | 18:59,483,335 | A/G | — | uncertain significance |
| rs140910064 | 18:59,483,368 | C/T | — | uncertain significance |
| rs1395334960 | 18:59,483,390 | G/T | — | uncertain significance |
| rs1343873145 | 18:59,483,395 | A/G | — | uncertain significance |
| rs2511614169 | 18:59,483,423 | T/C | — | uncertain significance |
| rs147542758 | 18:59,483,484 | G/A | — | likely benign |
| rs370262709 | 18:59,483,501 | C/T | — | uncertain significance |
| rs772487156 | 18:59,483,510 | C/T | — | uncertain significance |
| rs753556461 | 18:59,483,531 | C/T | — | uncertain significance |
| rs777583010 | 18:59,483,534 | G/A | — | uncertain significance |
| rs767426822 | 18:59,483,633 | G/A | — | uncertain significance |
| rs551185325 | 18:59,523,377 | A/T | — | — |
| rs192695719 | 18:59,549,697 | C/T | regulatory region variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.