RNF212
ring finger protein 212
Summary
This gene encodes a RING finger protein that may function as a ubiquitin ligase. The encoded protein may be involved in meiotic recombination. This gene is located within a linkage disequilibrium block and polymorphisms in this gene may influence recombination rates. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2010]
Known Variants35 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs534161196 | 4:1,050,277 | C/G | — | likely benign |
| rs1717354468 | 4:1,050,616 | G/A | — | likely benign |
| rs899631668 | 4:1,050,633 | C/T | — | likely benign |
| rs60085185 | 4:1,050,636 | C/T | — | benign |
| rs3816474 | 4:1,050,653 | A/G | — | benign |
| rs192018387 | 4:1,051,097 | C/T | intron variant | — |
| rs57186616 | 4:1,052,100 | A/G | — | likely benign |
| rs11724371 | 4:1,052,125 | C/T | — | benign |
| rs2248083 | 4:1,052,166 | A/C | — | benign |
| rs2045065 | 4:1,052,488 | A/T | — | — |
| rs2534277428 | 4:1,066,804 | T/A | — | uncertain significance |
| rs146228753 | 4:1,066,842 | C/T | — | likely benign |
| rs763348421 | 4:1,066,935 | C/A | — | uncertain significance |
| rs371212537 | 4:1,066,940 | T/G | — | uncertain significance |
| rs1034164775 | 4:1,067,408 | G/A | — | uncertain significance |
| rs775966266 | 4:1,075,369 | T/C | — | uncertain significance |
| rs1670533 | 4:1,078,187 | G/A | intron variant | association |
| rs759535226 | 4:1,079,699 | A/G | — | uncertain significance |
| rs869025240 | 4:1,079,732 | A/G | — | uncertain significance |
| rs542773933 | 4:1,081,069 | T/A | — | — |
| rs1670534 | 4:1,087,265 | T/C | — | benign |
| rs60035268 | 4:1,087,487 | G/A | — | benign |
| rs146161994 | 4:1,090,592 | T/C | — | uncertain significance |
| rs2534597681 | 4:1,090,599 | A/G | — | uncertain significance |
| rs140128337 | 4:1,090,620 | G/A | — | uncertain significance |
| rs4045481 | 4:1,090,625 | G/A | splice region variant | — |
| rs3796619 | 4:1,095,281 | A/G | coding sequence variant | association |
| rs374134594 | 4:1,102,132 | T/A | — | uncertain significance |
| rs747767304 | 4:1,102,150 | G/A | — | uncertain significance |
| rs370043717 | 4:1,102,153 | C/T | — | uncertain significance |
| rs775848912 | 4:1,102,186 | T/G | — | uncertain significance |
| rs375409179 | 4:1,107,153 | G/A | — | uncertain significance |
| rs1270511487 | 4:1,107,204 | T/G | — | uncertain significance |
| rs78978823 | 4:1,107,245 | T/C | — | benign |
| rs62296477 | 4:1,107,478 | C/T | — | risk factor |
Gene information from NCBI Gene. Variant classifications from ClinVar.