RSU1
Ras suppressor protein 1
Summary
This gene encodes a protein that is involved in the Ras signal transduction pathway, growth inhibition, and nerve-growth factor induced differentiation processes, as determined in mouse and human cell line studies. In mouse, the encoded protein was initially isolated based on its ability to inhibit v-Ras transformation. Multiple alternatively spliced transcript variants for this gene have been reported; one of these variants was found only in glioma tumors. [provided by RefSeq, Jul 2008]
Known Variants20 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs7068341 | 10:16,634,299 | C/T | 3 prime UTR variant | — |
| rs2491838736 | 10:16,635,416 | G/T | — | uncertain significance |
| rs757675861 | 10:16,737,048 | C/T | — | likely benign |
| rs11254160 | 10:16,744,523 | G/A | intron variant | — |
| rs7916663 | 10:16,748,610 | G/A | intron variant | — |
| rs2356375 | 10:16,751,118 | G/C | — | — |
| rs4027773 | 10:16,751,164 | G/T | intron variant | — |
| rs200140782 | 10:16,794,544 | C/G | — | uncertain significance |
| rs200148474 | 10:16,794,565 | G/A | — | uncertain significance |
| rs759133204 | 10:16,794,624 | G/A | — | uncertain significance |
| rs1352398987 | 10:16,794,940 | C/G | — | uncertain significance |
| rs116907560 | 10:16,794,990 | C/T | — | uncertain significance |
| rs1303596198 | 10:16,796,880 | G/T | — | uncertain significance |
| rs369457885 | 10:16,806,457 | A/T | — | uncertain significance |
| rs557338857 | 10:16,817,529 | T/C | — | — |
| rs802171 | 10:16,856,685 | A/G | intron variant | — |
| rs812426 | 10:16,857,133 | C/T | — | — |
| rs59946283 | 10:16,858,370 | T/C | intron variant | — |
| rs1588555975 | 10:16,859,017 | T/C | — | uncertain significance |
| rs546283132 | 10:16,859,076 | G/C | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.