RTRAF
RNA transcription, translation and transport factor
Summary
Enables RNA binding activity; RNA polymerase II complex binding activity; and identical protein binding activity. Involved in negative regulation of protein kinase activity; positive regulation of transcription by RNA polymerase II; and tRNA splicing, via endonucleolytic cleavage and ligation. Located in microtubule cytoskeleton; nucleoplasm; and perinuclear region of cytoplasm. Part of tRNA-splicing ligase complex. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants2 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs569092349 | 14:52,459,774 | T/C | — | — |
| rs573999255 | 14:52,468,689 | C/T | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.